Analysis of phthalic acid esters in agricultural soils

Langová, Radka; Jarošová, Alžběta; Poláková, Šárka; Kos, Ivica

doi:10.1007/s10661-019-8052-5

Cited by 8 publications

(2 citation statements)

References 9 publications

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“…do potravin), nebo například z lékařského vybavení 15 . Výskyt ftalátů byl zjištěn ve vzduchu 16 , půdě 17,18 , sedimentech ze skládek 19 , v povrchových vodách 20,21 , ale také v potravinovém řetězci 22 , kde hlavním zdrojem kontaminace potravin ftaláty byly obalové materiály, se kterými přichází potraviny do přímého kontaktu 23 .…”

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Changes in the Concentration of Phthalic Acid Esters in the Plastic Materials of Vehicles During the Usage

et al. 2022

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The presence of dibutyl phthalate (DBP) and di-2-ethylhexyl phthalate (DEHP) was monitored in 16 automotive plastic samples (steering wheel, dashboard, seats, headrests, and air conditioning control). The plastic samples were obtained from a crashed vehicle that had been in operation for only one month. Phthalates were determined by HPLC. The first analysis was performed immediately after the sample preparation, the second one after 3 months of storage, the third one after 6 months of storage, the fourth one after 9 months of storage, and the fifth one after 15 months of storage. The average DBP concentrations ranged from 1.3 to 197.1 μg g–1 of plastic at the beginning, 1.7to 161.5 μg g–1 of plastic in the 3rd month, 0.5 to 78.9 μg g–1 of plastic in the 6th month, 2.3 to 123.3 μg g–1 of plastic in the 9th month, and 14.0 to 98.6 μg g–1 of plastic in the 15th month. The average DEHP concentrations ranged from 1,7 to 185,7 μg g–1 of plastic at the beginning, 3,9 to 45,4 μg g–1 of plastic in the 3rd month, 1,4 to 252,4 μg g–1 of plastic on the 6th month, 5,1 to 41,7 μg g–1 in the 9th month, and 2,3 to 87,5 μg g–1 in the 15th month. In particular, higher concentrations were found in soft plastics. An interesting finding is that the content of both phthalates (DBP and DEHP) was also present in leather materials. According to the comparison of phthalates concentrations during storage, it can be stated that phthalates concentration decreases with time and, after approximately 15 months of storage, concentrations decreased: for DBP by 20 to 90% (in 44% samples) and for DEHP by 30 to 90% (in 70% samples). For the other samples, the increase of both phthalates was probably due to depolymerisation of the plastics by UV exposure, temperature and storage time. Phthalates are human carcinogens and they can cause the death or tissue malformation. They are dangerous for liver function. The legislation of the Czech Republic and European Union has not yet dealt with these problems.

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Changes in the Concentration of Phthalic Acid Esters in the Plastic Materials of Vehicles During the Usage

et al. 2022

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“…Phthalate esters (PAEs) are a kind of synthetic plasticizer and are extensively used in plastic production to improve their plasticity and flexibility. , Among the various PAEs, di(2-ethylhexyl) phthalate (DEHP) is most frequently used in daily necessities and agricultural products as an important plasticizer . Due to no covalent bonding between DEHP and the plastic components, DEHPs are easily leached out as persistent pollutants existing in the environment, such as air, soil, water, and so on. , Finally, DEHPs are taken up by crops grown such as wheat kernel, rice, and vegetables in plastic film greenhouses − and then have harmful effects on human health through the food chain. A large number of studies have shown that DEHP could cause neurotoxicity, developmental toxicity, and reproductive toxicity. , New findings have been reported that DEHP could result in liver oxidative injury by inducing lipid peroxidation and decreasing catalase activities .…”

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confidence: 99%

Lycopene Prevents DEHP-Induced Liver Lipid Metabolism Disorder by Inhibiting the HIF-1α-Induced PPARα/PPARγ/FXR/LXR System

Zhao

Wang³

et al. 2020

J. Agric. Food Chem.

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phthalate (DEHP) is a widespread pollutant that badly affects animals and human health. Lycopene (LYC) has been used as a dietary supplement that has effective antioxidant and antiobesity functions. The present goal was to understand the molecular mechanisms of LYC preventing DEHP-induced lipid metabolism of the liver. The mice were intragastrically administered with LYC (5 mg/kg) and/or DEHP (500 mg/kg or 1000 mg/kg). Here, we found that LYC attenuated DEHP-caused hepatic histopathological lesions including steatosis. Hematological and biochemical analyses revealed that LYC ameliorated DEHP-caused liver function and lipid metabolism disorders. DEHP caused lipid metabolism disorders via activating the peroxisome proliferator activated receptor α/γ (PPARα/γ) signal transducer and Farnesoid X receptor (FXR)/liver X receptor (LXR) signaling pathway. As a major regulator of lipid metabolism, hypoxia-inducible factor-1α (HIF-1α) system was elevated with increased fatty degeneration under DEHP exposure. However, LYC could decrease the levels of HIF-1α/PPARα/PPARγ/FXR/LXR signaling pathway-related factors. Our research indicated that LYC could prevent DEHP-induced lipid metabolism disorders via inhibiting the HIF-1α-mediated PPARα/PPARγ/FXR/LXR system. This study may provide a possible molecular mechanism for fatty liver induced by DEHP.

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Residual status and source analysis of phthalate esters in Ulungur Lake, China

Wang

Zhou

et al. 2023

Environ Geochem Health

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Analysis of phthalic acid esters in agricultural soils

Cited by 8 publications

References 9 publications

Changes in the Concentration of Phthalic Acid Esters in the Plastic Materials of Vehicles During the Usage

Changes in the Concentration of Phthalic Acid Esters in the Plastic Materials of Vehicles During the Usage

Lycopene Prevents DEHP-Induced Liver Lipid Metabolism Disorder by Inhibiting the HIF-1α-Induced PPARα/PPARγ/FXR/LXR System

Residual status and source analysis of phthalate esters in Ulungur Lake, China

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