Analysis of phosphorus-containing hydrolytic products of organophosphorus insecticides in water

Daughton, Christian G.; Crosby, Donald G.; Garnas, Richard L.; Hsieh, Dennis P. H.

doi:10.1021/jf60204a015

Cited by 46 publications

(11 citation statements)

References 20 publications

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“…However, salt addition had an adverse effect on the overall efficiency of the method and was therefore abandoned. In contrast to our observations, enhancement of the extraction or adsorption processes of DAP with salt addition was reported in some earlier work [17,19,20,46]. With the automated SPE, we achieved much lower flow rates (0.4 ml/min) of urine through the column bed than were possible with manual SPE.…”

Section: Resultscontrasting

confidence: 97%

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Measurement of human urinary organophosphate pesticide metabolites by automated solid-phase extraction, post extraction derivatization, and gas chromatography–tandem mass spectrometry

Alwis

Needham

Barr

2006

Journal of Chromatography B

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Section: Resultscontrasting

confidence: 97%

“…The compounds were protonated by lowering the pH to <1.25 (pK a for DMP = 1.25) [17,46,47] with HCl for efficient retention of DAPs in the SPE column. Although in previous studies [19,20] low recoveries were observed with HCl as the acidifying agent compared with acetic acid, our observation was in complete contrast.…”

Section: Resultsmentioning

confidence: 99%

Measurement of human urinary organophosphate pesticide metabolites by automated solid-phase extraction, post extraction derivatization, and gas chromatography–tandem mass spectrometry

Alwis

Needham

Barr

2006

Journal of Chromatography B

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“…To determine water-soluble products of organophosphate breakdown, samples were treated with diazomethane by the method of Daughton et al (5). The derivatized products were extracted twice with ethyl acetate and dried with anhydrous Na2SO4 over glass wool before gas chromatography.…”

Section: Methodsmentioning

confidence: 99%

Microbial cleavage of various organophosphorus insecticides

Rosenberg¹,

Alexander²

1979

Appl Environ Microbiol

117

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Bacteria able to utilize Aspon, Azodrin, Dasanit, diazinon, malathion, Orthene, parathion, Trithion, dimethoate, Dylox, methyl parathion, and Vapona as sole phosphorus sources were isolated from soil and sewage. Individual isolates used from 3 to 10 of these insecticides as sole phosphorus sources. The extent of growth of two Pseudomonas strains in media containing diazinon and malathion was in the range expected from the amount of insecticide supplied, and their proliferation resulted in disappearance of the chemical. Resting cells of the pseudomonads derived from cultures grown on diazinon or malathion but not orthophosphate caused extensive destruction of these two organophosphates in the presence or absence of chloramphenicol. Extracts of the two bacteria derived from organophosphate-grown cultures catalyzed the disappearance of Aspon, Azodrin, Dasanit, diazinon, malathion, Orthene, parathion, and Trithion but not dimethoate, Dylox, methyl parathion, and Vapona. Results from gas chromatographic analysis suggested that the extracts formed dimethyl phosphate from azodrin, dimethyl phosphorodithioate from malathion, diethyl phosphorodithioate from Trithion, and diethyl phosphorothioate from Dasanit, diazinon, and parathion. Dimethyl phosphate, dimethyl phosphorothioate, dimethyl phosphorodithioate, diethyl phosphate, and diethyl phosphorothioate were not used by the pseudomonads as sole phosphorus sources.

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“…With one exception (the October concentrate in TAIOO), our dHzO and stored dHzO LeBel et a1 [1979] demonstrated that XAD-2 resin effectively concentrated all 16 organophosphorus pesticides that they tested, and other workers also have shown the usefulness of XAD-2 and XAD-4 resins for concentrating agricultural chemicals [Daughton et al, 1976;Berkane et al, 19771. In a study that combined column chromatography with mutagenicity tests, Chriswell et a1 [1979] studied the ability of 16 types of resins to concentrate mutagens from four Iowa water utilities.…”

Section: Discussionmentioning

confidence: 92%

Mutagenicity of municipal water obtained from an agricultural area

et al. 1981

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We have studied the mutagenicity of the water from Lake Bloomington and of the tap water that is made from the lake water. The lake, which is the source of drinking water for Bloomington, Illinois (pop. 44,000), is surrounded by land that is farmed intensively--being mainly in maize and soybeans. Samples were collected monthly from May through October 1979 and concentrated 3,000X with XAD-2 resin. Nearly all of the lake and tap water concentrates were mutagenic in Salmonella typhimurium TA98 and TA100 in the presence of S-9 mix, and the May tap water concentrate was highly mutagenic. In addition, many of the concentrates were toxic to the bacteria in the absence of S-9 mix. Chemical analysis of the highly mutagenic tap water concentrate from May revealed the presence of a number of organic contaminants that were absent from control concentrates prepared from deionized and distilled treated-well water. In addition, unconcentrated lake and tap water were tested in a reverse-mutation test in maize (Zea mays); no mutagenicity was detected. This study indicates that the contamination of drinking water with agricultural and/or industrial chemicals may result in a potential health hazard.

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Analysis of phosphorus-containing hydrolytic products of organophosphorus insecticides in water

Cited by 46 publications

References 20 publications

Measurement of human urinary organophosphate pesticide metabolites by automated solid-phase extraction, post extraction derivatization, and gas chromatography–tandem mass spectrometry

Measurement of human urinary organophosphate pesticide metabolites by automated solid-phase extraction, post extraction derivatization, and gas chromatography–tandem mass spectrometry

Microbial cleavage of various organophosphorus insecticides

Mutagenicity of municipal water obtained from an agricultural area

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