Analysis of pesticide residues by fast gas chromatography in combination with negative chemical ionization mass spectrometry

Application of Fast Gas Chromatography–Mass Spectrometry in Combination with the QuEChERS Method for the Determination of Pesticide Residues in Fruits and Vegetables

“…In another paper, 20 pesticides were determined in baby food using GC-MS with single quadrupole in 8 min, testing the capabilities of the QuEChERS procedure versus other sample preparation methods (Hercegová et al 2006). The possibility of working in negative chemical ionization mode was also tested for the determination of 25 pesticides in fruits and vegetables treated by QuEChERS with a chromatographic run time of only 11 min (Húšková et al 2009). In general terms, several fast GC methods have been developed and validated for pesticides but, in most cases, for quite a limited number of compounds and sample matrices.…”

Fast Gas Chromatography and Its Use in Pesticide Residues Analysis

“…For illustration the chromatograms of the target ions of the pesticides analyzed by fast GC-MS in the SIM mode in the real sample extracts, in NCI and EI ionization modes, are given in Fig. 7 (Húšková et al, 2009). It is evident from the chromatograms that there are interferences in EI mode which are dependent on the matrix (orange, lettuce), whereas in NCI mode very "clean" chromatograms with high responses of analytes without influence from the matrices were obtained.…”

“…Numbering of peaks is identical with the number of compounds given in the Table 4. (Húšková et al, 2009 -coefficients of determination, LCL-the lowest calibration level, RSDAi -relative standard deviation (6 replicates), LOD -limit of detection calculated as 3:1 S/N ratio from calibration measurements, LOQ -limit of determination calculated as 10:1 S/N ratio from calibration measurements. Table 4.…”

“…Application of fast GC set-up using narrow-bore column (0.15 mm I.D.) in combination with MS detector in NCI mode was introduced and compared to fast GC-MS with electron ionization by Húšková et al, 2009. Multi-residue method of 25 pesticides belonging to different groups (organochlorines, organophosphates, pyrethroids, dicarboximides, 2,6-dinitroaniline, triazinone, substituted urea, phthalamide, cyclodiene, triazole, imidazole), varying in polarity, volatility and other physicochemical properties from non-fatty fruit and vegetable matrices based on fast GC with quadrupole NCI-MS was developed and verification of the method was realized.…”

“…However, GPC is considered as universal method for cleaning-up purposes of a wide range of matrices and multi-class pesticides, the time analysis and the cost is too high. According to Húšková et al, 2009, the batch of 6 samples in parallel is prepared within 46 min with the fast GC with narrow-bore column single run time 11.45 min. QuEChERS technique is the most effective technique employing the clean-up step.…”