Analysis of organophosphorus flame retardants in environmental and biotic matrices using on-line turbulent flow chromatography-liquid chromatography-tandem mass spectrometry

Giulivo, Monica; Capri, E.; Eljarrat, Ethel; Barceló, Damià

doi:10.1016/j.chroma.2016.10.042

Cited by 61 publications

(38 citation statements)

References 24 publications

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“…The instrumental LODs were between 0.1 and 0.6 ng/mL (0.5 and 3 injected pg), and instrumental LOQs were between 0.4 and 1.9 ng/mL (2 and 9.5 injected ng) (Supporting Information Table S3). These values were similar to those reported when determining PFRs by LC–MS/MS elsewhere .…”

Section: Resultssupporting

confidence: 89%

Determination of organophosphate flame retardants in soil and fish using ultrasound‐assisted extraction, solid‐phase clean‐up, and liquid chromatography with tandem mass spectrometry

Lorenzo

Campo

Picó

2018

J of Separation Science

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A solid-liquid extraction method in combination with high-performance liquid chromatography and tandem mass spectrometry was developed and optimized for extraction and analysis of organophosphorus flame retardants in soil and fish. Methanol was chosen as the optimum extraction solvent, not only in terms of extraction efficiency, but also for its broader analyte coverage. The subsequent clean-up by solid-phase extraction is required to eliminate matrix coextractives and reduce matrix effects. Recoveries of the optimized method were 50-121% for soil and 47-123% for biota, both with high precision (RSDs <12% in soil and <23% in biota). The method limits of detection ranged from 0.06 to 0.20 ng/g dry weight and between 0.02 and 0.30 ng/g wet weight for soil and biota samples, respectively. However, samples with a high lipid content produce several problems as solid-phase extraction cartridge clogging that increase variability and analysis time. The method was successfully applied for the determination of organophosphorus flame retardants in soil and fish from L'Albufera Natural Park (Valencia, Spain). Target compounds were detected in all soil and fish samples with values varying from 13.8 to 89.7 ng/g dry weight and from 3.3 to 53.0 ng/g wet weight, respectively.

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Section: Resultssupporting

confidence: 89%

Determination of organophosphate flame retardants in soil and fish using ultrasound‐assisted extraction, solid‐phase clean‐up, and liquid chromatography with tandem mass spectrometry

Lorenzo

Campo

Picó

2018

J of Separation Science

View full text Add to dashboard Cite

show abstract

“…However, owing to their high diffusivity, biomass recalcitrance, bioenrichment and biotoxicity, they were discontinued gradually. Organophosphorus flame retardants (PFRs) became of interest for their flame retardancy owing to their excellent physicochemical properties, technical characteristics and low cost . Presently, PFRs have been diffusely applied in furniture manufacturing, the textile industry, electronics, the chemical industry, polyurethane foam and plasticizers .…”

Section: Introductionmentioning

confidence: 99%

“…PFRs pollute the air, water and soil through volatilization, leaching or abrasion; additionally, vestigial PFRs were also found in aquatic products, such as fish . The bioaccumulation of PFRs resulted in hepatic lipid metabolism and serum hypertriglyceridaemia by inhalation, ingestion and absorption . To reduce the pollution of PFRs, the EU announced restrictions on the use of halogen flame retardants; in addition, some PFRs have been prohibited from being utilized in the USA .…”

Section: Introductionmentioning

confidence: 99%

“…Organophosphorus flame retardants (PFRs) became of interest for their flame retardancy owing to their excellent physicochemical properties, technical characteristics and low cost. 3 Presently, PFRs have been diffusely applied in furniture manufacturing, the textile industry, electronics, the chemical industry, 4 polyurethane foam and plasticizers. 5,6 The worldwide consumption of PFRs was estimated to be 150 000 t. 7 PFRs pollute the air, 8 water 9 and soil 10 through volatilization, leaching or abrasion; 11 additionally, vestigial PFRs were also found in aquatic products, such as fish.…”

Section: Introductionmentioning

confidence: 99%

“…12,13 The bioaccumulation of PFRs resulted in hepatic lipid metabolism and serum hypertriglyceridaemia by inhalation, ingestion and absorption. 3,14 To reduce the pollution of PFRs, the EU announced restrictions on the use of halogen flame retardants; 15 in addition, some PFRs have been prohibited from being utilized in the USA. 16 Therefore, the determination of PFRs becomes of interest in the inspection and detection of commodities and food, especially for aquatic products.…”

Section: Introductionmentioning

confidence: 99%

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