Analysis of Motor Behavior and Neuroplasticity in an Experimental Model of Hemiplegia Treated With Transcranial Therapy

Abstract

Stroke is one of the leading causes of death worldwide; its severity is associated with high death rates and motor, cognitive, and sensory . Several interventions have been proposed in recent years to prevent and primarily treat stroke. LED stands out as one of these interventions; it indicates promising results because it stimulates cellular metabolism, increasing the cellular regenerative potential, and promoting . Thus, the present study evaluated the effects of 630 nm LED in animals submitted to ischemic stroke by analyzing and motor behavior. This was an experimental study with a controlled qualitative and quantitative intervention, with a sample of 30 male Wistar Rattus divided into two groups: a control group and treated group, consisting of 15 animals each. The experimental time points were 3, 7, and 21 days of treatment. All animals were submitted to surgery for the implantation of an electrode and subsequent electrolytic lesion. The quantitative results in the three experimental time points indicate treatment superiority using the 630 nm LED compared to the control group. The findings also showed increased tissue in the treated group at 3, 7, and 21 days of treatment when compared to the control group. Hence, the results suggest that the 630 nm LED guided treatment in the experimental time points of 3, 7, and 21 days was superior to those in the control group, showing animals with increased motor response according to the apprehension test, and improved according to the evaluation.