Analysis of Integrated Optofluidic Lab-on-a-Chip Sensor Based on Refractive Index and Absorbance Sensing

Krishnaswamy, Narayan; Srinivas, T.; Rao, G. Mohan; Varma, Manoj M.

doi:10.1109/jsen.2013.2243429

Cited by 12 publications

(1 citation statement)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Also, for the cases where a dynamic range is not explicitly listed, values have been obtained from figures within the publications (the best dynamic range is noted for groups of publications). Furthermore, while the entries in Table 3 and the discussion below primarily focus on experimental OLED-OPD-LoC systems, it is worth noting that some work has been done on modelling these systems to extract ultimate limits of detection [103,104]. Banerjee, Pais and coworkers continued their earlier work by replacing their halide lamp excitation source with a green-emitting Alq 3 OLED [105][106][107].…”

Section: Fully Integrated Oled/opd Lab-on-a-chip Systemsmentioning

confidence: 99%

Integration of Organic Light Emitting Diodes and Organic Photodetectors for Lab-on-a-Chip Bio-Detection Systems

2014

View full text Add to dashboard Cite

The rapid development of microfluidics and lab-on-a-chip (LoC) technologies have allowed for the efficient separation and manipulation of various biomaterials, including many diagnostically relevant species. Organic electronics have similarly enjoyed a great deal of research, resulting in tiny, highly efficient, wavelength-selective organic light-emitting diodes (OLEDs) and organic photodetectors (OPDs). We consider the blend of these technologies for rapid detection and diagnosis of biological species. In the ideal system, optically active or fluorescently labelled biological species can be probed via light emission from OLEDs, and their subsequent light emission can be detected with OPDs. The relatively low cost and simple fabrication of the organic electronic devices suggests the possibility of disposable test arrays. Further, with full integration, the finalized system can be miniaturized and made simple to use. In this review, we consider the design constraints of OLEDs and OPDs required to achieve fully organic electronic optical bio-detection systems. Current approaches to integrated LoC optical sensing are first discussed. Fully realized OLED-and OPD-specific photoluminescence detection systems from literature are then examined, with a specific focus on their ultimate limits of detection. The review highlights the enormous potential in OLEDs and OPDs for integrated optical sensing, and notes the key avenues of research for cheap and powerful LoC bio-detection systems.

show abstract