Analysis of Indications and Results in Liver Retransplantation: Is Late Retransplantation Worthwhile?

Cabrera, Jennifer Triguero; Carroll, Natalia Zambudio; González-Martínez, Silvia; Quintana, R.; Granero, Karim Muffak; Massare, A. Becerra; Herrera, T. Villegas; Moral, Jesús María Villar del

doi:10.1016/j.transproceed.2017.12.055

Cited by 7 publications

(1 citation statement)

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“…Keeping retransplantation as the last option is justified by the feasibility of conservative management of LHAT, current organ shortage and inherent morbidity and mortality of a second transplantation. Survival of retransplantated patients in this study was comparable to that of larger series of retransplantation . However, it should be mentioned that the existence of LHAT might increase the degree of technical difficulty, compared to retransplantation in others indications.…”

Section: Discussionsupporting

confidence: 62%

Late hepaticartery thrombosis after liver transplantation: which strategy? A single‐center retrospective study

et al. 2019

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Summary The management of late hepatic artery thrombosis (LHAT) after liver transplantation (LT) is not codified. The objective of this study was to retrospectively evaluate outcomes after LHAT. All patients with HAT diagnosed 3 months or later after LT on computed tomography between 1993 and 2017 were included. Our policy was to apply a conservative management for asymptomatic or mild symptomatic patients and reserve retransplantation to symptomatic patients with diffuse cholangitis or liver abscess. A total of 56 patients were analyzed. LHAT diagnosis was made after a median interval of 48 months from LT (ranging from 3 to 368.3). At diagnosis, 28 (50%) patients were asymptomatic, 10 (17.8%) had mild symptoms (transient acute cholangitis), and 18 (32.1%) had severe complications. Asymptomatic patients experienced a 5‐year graft survival of 57% vs. 40% in those with mild symptoms and 11% in those with severe complications (P < 0.001). However, there was no difference in overall patient survival between groups. Our results suggest that conservative management of LHAT for asymptomatic patients or patients with mild complications is safe. Retransplantation should be reserved to patients with severe biliary complications.

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Section: Discussionsupporting

confidence: 62%