Analysis of Incidence of Bulla Formation After Tattoo Treatment Using the Combination of the Picosecond Alexandrite Laser and Fractionated CO2 Ablation

Au, Sonoa; Liolios, Ana Marie; Goldman, Mitchel P.

doi:10.1097/dss.0000000000000244

Cited by 24 publications

(19 citation statements)

References 6 publications

(8 reference statements)

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“…The definitions of the outcome measures varied among the studies. Seven trials explored the use of either 1064 nm (Nd:YAG) [15], 755 nm [16,18,20], 795 nm [13], 758 nm [14], or frequency-doubled 1064/532 nm [17] lasers for the treatment of mainly black and blue tattoos. One of the trials explored the use of frequency-doubled 1064/532-nm lasers for the treatment of yellow tattoos [19].…”

Section: Resultsmentioning

confidence: 99%

“…Eight studies fulfilled the eligibility criteria, including two non-randomized controlled trials in animal models [13,14] and clinical studies with 160 participants bearing 182 tattoos. The clinical studies included one non-randomized controlled trial [15], two noncontrolled prospective trials [16,17], two case series [18,19], and one retrospective case-control study that only investigated side effects [20]. The trials' characteristics are detailed in Tables 1 and 2.…”

Section: Resultsmentioning

confidence: 99%

“…Rates per patient for the 755-nm picosecond laser in different studies were 0 [16], 10 % [18], and 32 % [20]. In one trial [20], adding a fractionated CO 2 laser to the 755-nm laser treatment reduced the rate of bulla formation from 32 to 0 %. The frequency-doubled 1064/532-nm laser was associated with 0 [17] and 50 % [19] bulla formation.…”

Section: Adverse Effectsmentioning

confidence: 97%

“…Two trials used just one session [18,20]. One trial used a fixed number of four sessions [15], and three trials allowed up to 7-10 sessions, with averages of 3.3 [19], 4.25 [16], and 6.5 [17].…”

Section: Number Of Laser Sessions Requiredmentioning

confidence: 99%

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Picosecond lasers for tattoo removal: a systematic review

et al. 2016

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Given that the pigment particles in tattoos have a relaxation time of <10 ns, picosecond lasers would be expected to be more effective than nanosecond lasers in tattoo removal. To systematically review the evidence regarding the effectiveness and safety of picosecond lasers for tattoo removal, Pubmed, Cochrane Central Register of Controlled Trials (CENTRAL), ClinicalTrials.gov, and reference lists were searched for relevant trials. The primary outcome was >70 % clearance of tattoo pigment. Secondary outcomes were 90-100 % clearance of tattoo pigment, number of laser sessions required, and adverse effects. Eight trials were included, six with human participants (160 participants) and 2 with animal models. Seven of the eight trials explored the usage of either 755, 758, 795, 1064, or 1064/532-nm picosecond lasers for black and blue ink tattoos. In the human trials, 69-100 % of tattoos showed over 70 % clearance of pigment after 1-10 laser treatments. Reported side effects included pain, hyperpigmentation and hypopigmentation, blister formation and transient erythema, edema, and pinpoint bleeding. Included articles varied in type of laser investigated, mostly non-comparative studies and with a medium to high risk of bias. There is sparse evidence that picosecond lasers are more effective than their nanosecond counterparts for mainly black and blue ink tattoo removal, with minor side effects.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Adverse Effectsmentioning

confidence: 97%

Section: Number Of Laser Sessions Requiredmentioning

confidence: 99%

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Picosecond lasers for tattoo removal: a systematic review

et al. 2016

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“…Anecdotal case reports have documented better responses to combined treatment with a fractionated CO 2 laser and QS ruby laser compared with QS laser treatment alone, and this method may reduce the risk of bulla formation (Weiss & Geronemus, 2011). In a retrospective study of 81 patients, 30% of patients treated with the picosecond 755 nm alexandrite laser alone developed blistering, compared with none of the patients treated with both modalities (Au, Liolios, & Goldman, 2015).…”

Section: Dear Editormentioning

confidence: 99%

Clearance of facial tattoo with triple-wavelength picosecond laser and fractionated carbon dioxide laser

Rivera¹,

Zaldo²,

Jauregui³

et al. 2018

Dermatologic Therapy

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A 34-year-old Hispanic woman presented to our clinic with a 2-week history of facial tattoo with the aim of recreating the appearance of "freckles" on her face. The patient was distressed and mentioned negative impacts on personal and professional relationships. At examination, multiple small, hyperpigmented, brownish macules were noted concordant with polychromatic professional facial tattoo with the presence of a moderate amount of reddish-brown ink ( Figure 1). Therefore, triple-wavelength picosecond laser in combination with fractionated laser seems to be a safe and effective therapeutic approach in a dark-skinned patient with a tattoo localized in a cosmetically relevant area. FUNDING INFORMATIONThis study has no funding source. The authors are responsible for the accuracy of the information presented.

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Comparative Evaluation of 15 Laser and Perfluorodecalin Combinations for Tattoo Removal

et al. 2019

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Background and ObjectivesWe present a case of laser tattoo removal treated with 15 different combinations using picosecond 1064 nm, picosecond 755 nm, nanosecond 755 nm, and a fractionated CO2 laser, both with and without a perfluorodecalin (PFD) patch to ascertain the most effective approach.Study Design/Materials and MethodsA single lower extremity black tattoo was divided into 15 treatment sections allowing for testing of various laser and PFD combinations. Sectioned treatment was conducted until a treatment superiority was noted.ResultsAfter two sessions using sectioned combination treatments with a 4‐week interval clinically significant results were produced.ConclusionsThe combination of picosecond 1064 nm, picosecond 755 nm, and a fractionated CO2 laser without the PFD patch showed superior clinical improvement over the other combinations. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.

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Analysis of Incidence of Bulla Formation After Tattoo Treatment Using the Combination of the Picosecond Alexandrite Laser and Fractionated CO2 Ablation

Cited by 24 publications

References 6 publications

Picosecond lasers for tattoo removal: a systematic review

Picosecond lasers for tattoo removal: a systematic review

Clearance of facial tattoo with triple-wavelength picosecond laser and fractionated carbon dioxide laser

Comparative Evaluation of 15 Laser and Perfluorodecalin Combinations for Tattoo Removal

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