Analysis of in vitro reaction layers formed on 48S4 glass for applications in biomaterial field

Mami, M.; Oudadesse, Hassane; Dorbez-Sridi, Rachida; Dietrich, Elodie; Rocherullé, Jean

doi:10.1051/epjap:2007141

Cited by 3 publications

(2 citation statements)

References 25 publications

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“…Bands were assigned on the basis of published data [8,9]. From the tabulated assignments it is clear that a silicarich layer is present, together with a carbonate-containing hydroxyapatite layer [10].…”

Section: Resultsmentioning

confidence: 99%

Comparison of the Chemical Reactivity and Bioactivity of Two Bioactive Glasses 47S6 and 48S4

Oudadesse

Mami

Dorbez-Sridi

et al. 2008

KEM

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This work is focused on the bioactive glasses obtained by melting and rapid quenching. Two glasses with mineral composition of: 47% SiO2 - 26% CaO - 21% Na2O - 6% P2O5 and 48% SiO2 - 30% CaO - 18% Na2O - 4% P2O5 were investigated. The aim of this study was to establish the kinetics of HCAp layer formation “in vitro” and to control the adhesion and proliferation cells of the two glasses in contact with osseous cells. Obtained results permit to evaluate their chemical reactivity and their bioactivity after immersion in the SBF-K9. Ionic exchanges between biomaterials and SBF liquid during the “in vitro” experiments highlight the differences of the chemical reactivity and bioactivity of 47S6 and 48S4. The structural basis for the effect of cristallinity on the rates of HCA formation in vitro in favour of glasses was also established. The melt derived 47S6 and 48S4 glasses offer to surgeons new compositions with different bioactivity kinetic that bioglassÒ 45S6 and can be adaptable in some other bony pathology.

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Section: Resultsmentioning

confidence: 99%

Comparison of the Chemical Reactivity and Bioactivity of Two Bioactive Glasses 47S6 and 48S4

Oudadesse

Mami

Dorbez-Sridi

et al. 2008

KEM

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“…The different studied glasses belong to the SiO 2 ÀCaOÀNa 2 OÀ P 2 O 5 system and are doped with atomic elements like magnesium, zinc and strontium. [16][17][18][19] These elements have been introduced as trace elements and are of high physiological interest in the biomedical field. [20] 29 Si and 31 P MAS-NMR was used to characterize the local environment and determine the influence of doping elements on the chemical reactivity of glasses and the formation of hydroxyapatite.…”

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confidence: 99%

In vitro Chemical Reactivity of Doped Bioactive Glasses: an Original Approach by Solid‐State NMR Spectroscopy

et al. 2009

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International audienceThe control of the in vitro and in vivo bioactivity, as well as the chemical reactivity of melt-derived glasses is an important state in the biomaterials field. The present work explores the local structure of bioactive glasses before and after in vitro assays in simulated body fluid. This study by solid-state MAS-NMR constitutes an original approach to the understanding of the bioactivity process

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Hybrid Magnetic Nanostructures For Cancer Diagnosis And Therapy

Ardelean

Ficai

Sönmez

et al. 2019

ACAMC

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Cancer is the second disease in the world from the point of view of mortality. The conventional routes of treatment were found to be not sufficient and thus alternative ways are imposed. The use of hybrid, magnetic nanostructures is a promising way for simultaneous targeted diagnosis and treatment of various types of cancer. For this reason, the development of core@shell structures was found to be an efficient way to develop stable, biocompatible, non-toxic carriers with shell-dependent internalization capacity in cancer cells. So, the multicomponent approach can be the most suitable way to assure the multifunctionality of these nanostructures to achieve the desired/necessary properties. The in vivo stability is mostly assured by the coating of the magnetic core with various polymers (including polyethylene glycol, silica etc.), while the targeting capacity is mostly assured by the decoration of these nanostructures with folic acid. Unfortunately, there are also some limitations related to the multilayered approach. For instance, the increasing of the thickness of layers leads to a decrease the magnetic properties, (hyperthermia and guiding ability in the magnetic field, for instance), the outer shell should contain the targeting molecules (as well as the agents helping the internalization into the cancer cells), etc.

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Analysis of in vitro reaction layers formed on 48S4 glass for applications in biomaterial field

Abstract: International audienc

Cited by 3 publications

References 25 publications

Comparison of the Chemical Reactivity and Bioactivity of Two Bioactive Glasses 47S6 and 48S4

Comparison of the Chemical Reactivity and Bioactivity of Two Bioactive Glasses 47S6 and 48S4

In vitro Chemical Reactivity of Doped Bioactive Glasses: an Original Approach by Solid‐State NMR Spectroscopy

Hybrid Magnetic Nanostructures For Cancer Diagnosis And Therapy

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