Analysis of in vitro antioxidant activity of Caryota urens L. leaves: A traditional natural remedy

Mamun, Abdullah Al; Khanum, Sayema; Begum, Yesmin; Alam, Md. Shah

doi:10.12980/jclm.4.2016j6-65

Cited by 15 publications

(7 citation statements)

References 51 publications

(33 reference statements)

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“…The electron gifting capability of the medicinal plant is most widely determined by DPPH radical scavenging test owing to its reliability [35]. In this test, purplecolored solution of DPPH radical by accepting electrons converted to discolor DPPH-H.…”

Section: Discussionmentioning

confidence: 99%

Inspection of Phytochemical Content and In Vitro Antioxidant Profile of Gnaphalium luteoalbum L.: An Unexplored Phytomedicine

Uddin

Begum

et al. 2017

J. Pharm. Nutr. Sci.

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Background: Oxidative stress is intensely linked with several pathological manifestations. Searching for medicinal plant with the superior safety profile for the treatment of oxidative stress related disorders are ongoing due to multiple unwanted effects associated with synthetic antioxidants. Therefore the purpose of this study was to examine the phytochemical content, in vitro antioxidant potentiality of crude methanol extract (CME), carbon tetrachloride fraction (CTF), petroleum ether fraction (PEF), chloroform fraction (CLF) and ethyl acetate fraction (EAF) of aerial parts of Gnaphalium luteoalbum (GL) L. Methods: The aerial parts of the GL were extracted with methanol followed by fractionation using carbon tetrachloride, petroleum ether, chloroform and ethyl acetate. The phytochemical screening of this plant was performed by using standard methods to evaluate the existence of alkaloids, carbohydrates, phenols, flavonoids, saponins, tannins, terpenoids and fixed oils. Antioxidant potentiality was estimated by, 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl (OH) and nitric oxide (NO) radical scavenging tests. Total antioxidant capacity (TAC), total phenolic content (TPC) and total flavonoid content (TFC) were also measured. Results: Phytochemical analysis of the aerial parts of GL confirmed the presence of carbohydrates, phenols, flavonoids and saponins in crude extract and its all fractions. The CME showed the highest scavenging activity (43.28%) with IC50 of 398.49 µg/mL in the DPPH radical scavenging test. The IC50 values of EAF, CME were statistically significant (P < 0.05, P < 0.01) with respect to ascorbic acid (ACA). For OH and NO radical scavenging tests maximum scavenging (48.39%, 69.64%) was also reported for CME compared to CTF, PEF, CLF and EAF. Compared to ACA, in case of OH and NO radical scavenging activities the IC50 values of CME were markedly significant (P < 0.01, P < 0.05). In the TAC test, CME showed the highest antioxidant activity (absorbance, 2.6 nm) related to other fractions. TPC was found to be the highest in the CME (115.96 mg of gallic acid equivalent/g of dried extract) rather than other fractions. The ranking order of CTF, PEF, CLF, EAF and CME for TFC was 48.67 < 55.75 < 65.29 < 71.35 < 82.29 mg quercetin equivalent/g of dried extract. Conclusion: The existing study suggested that CME of the aerial parts of GL can be used as a natural source of antioxidant which might be effective towards preventing or slowing oxidative stress related disorders.

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Section: Discussionmentioning

confidence: 99%

Inspection of Phytochemical Content and In Vitro Antioxidant Profile of Gnaphalium luteoalbum L.: An Unexplored Phytomedicine

Uddin

Begum

et al. 2017

J. Pharm. Nutr. Sci.

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“…Natural products mainly plants have been used from ancient civilization in human medicine as therapeutic agents [37,38]. Natural compounds have been described to interface with different molecular and cellular targets such as hormone, transmembrane transporters, enzymes and neurotransmitter receptors [39,40].…”

Section: Discussionmentioning

confidence: 99%

In Vivo Screening for Analgesic and Anti-Inflammatory Activities of Syngonium podophyllum L.: A Remarkable Herbal Medicine

Hossain

Uddin

Kabir

et al. 2017

ARRB

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Aims: Algesia and inflammation are strongly connected with several pathological conditions. Searching for natural healing agents with a better safety profile for the treatment of these conditions are ongoing due to multiple unwanted effects associated with synthetic pharmaceuticals. Therefore the purpose of this study was to analyse the analgesic and anti-inflammatory activities of the Original Research Article

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“…Previous reports suggest that phenolic and flavonoid compounds (gallic acid, caffeic acid, p -coumaric acid, quercetin, rutin and catechin) in plants possess strong antioxidant activity that might contribute to antimicrobial potential [ 33 , 43 ]. The disc diffusion method was employed for the determination of antimicrobial activity of plant extracts against different human pathogens.…”

Section: Discussionmentioning

confidence: 99%

In Vitro Anti-Oxidant and Anti-Microbial Potentiality Investigation of Different Fractions of Caryota urens Leaves

et al. 2016

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Background: Caryota urens is a member of the Arecaceae family and a common plant in the Southeast Asian region. This plant has been reported as an anti-microbial agent in recent years. Thus, we aimed to find out the MIC (minimum inhibitory concentration) against different pathogenic microorganism. Methods: The leaves of C. urens were extracted and fractioned using different reagents (chloroform, n-hexane and carbon tetrachloride). Disc diffusion method was implemented for the assessment of in vitro anti-microbial potency (500 and 250 µg/disc). Result: The entire fraction showed good effect (with the zone of inhibition 19–25 mm) against both gram positive (Bacillus subtilis, Bacillus megaterium, Bacillus cereus, Sarina lutea) and gram negative (Vibrio mimicus, Shigella boydii, Escherichia coli, Pseudomonas aeruginosa) bacterial pathogens and fungal strains (Aspergillus niger, Saccharomyces cerevisiae). The plants also possess effective free radical scavenging potency with an IC50 of 130.32 µg/mL. Conclusion: This finding reflects a link between the presence of anti-oxidative material and a substantial anti-microbial activity, and substantiates all previous claims against C. urens.

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Analysis of in vitro antioxidant activity of Caryota urens L. leaves: A traditional natural remedy

Cited by 15 publications

References 51 publications

Inspection of Phytochemical Content and In Vitro Antioxidant Profile of Gnaphalium luteoalbum L.: An Unexplored Phytomedicine

Inspection of Phytochemical Content and In Vitro Antioxidant Profile of Gnaphalium luteoalbum L.: An Unexplored Phytomedicine

In Vivo Screening for Analgesic and Anti-Inflammatory Activities of Syngonium podophyllum L.: A Remarkable Herbal Medicine

In Vitro Anti-Oxidant and Anti-Microbial Potentiality Investigation of Different Fractions of Caryota urens Leaves

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