Analysis ofPogostemon cablinfrom pharmaceutical research to market performances

Abstract

P. cablin has beneficial therapeutic potential as an effective adaptogenic herbal remedy in clinic. Molecular mechanisms and active targets of P. cablin compounds, the qualitative and quantitative standard of P. cablin, as well as novel drug delivery systems of P. cablin, would be developed.

Patchouli oil isolated from the leaves of Pogostemon cablin ameliorates ethanol-induced acute liver injury in rats via inhibition of oxidative stress and lipid accumulation

“…18 Pogostemon cablin (Blanco) Benth (Labiatae), a traditional Chinese herb with aromatic characteristic, is cultivated in Asia extensively, and is always used for the treatment of vomiting, inuenza, exogenous fever, gastrointestinal disease and liver stagnation. 19,20 Patchouli oil (PO) is the extractive from the dry leaves of Pogostemon cablin. 21 PO nowadays is widely applied as an additive in health products industry and food industry.…”

Gastroprotective effect and mechanism of patchouli alcohol against ethanol, indomethacin and stress-induced ulcer in rats

“…Pogostemonis Herba has been widely applied for gastrointestinal disease in China, Japan, and Korea as an aromatic stomachic to improve impairment of the digestive system [4]. To date, Pogostemonis Herba has been used as the main compositions in more than 40 kinds of traditional Chinese medicine (TCM) preparations, such as Huoxiang Zhengqi Shui and Po Chai Pills, which are mainly used for acute gastrointestinal disorders [5]. Modern researches have demonstrated that the aqueous extract of Pogostemonis Herba could effectively protect the intestinal barrier function [6], relieve gastrointestinal spasms [7] and improve the digestion function [8].…”

Patchouli Alcohol, a Compound from Pogostemon cablin, Inhibits Obesity

“…24 Pogostemon cablin (also called patchouli) is a well-known essential oil in Chinese medication and its proposed therapeutic effects include antiviral, antioxidative, analgesic, anti-inflammatory activities, and intestinal barrier function protection. 25 One of the most recently proposed health benefit properties by essential oils is metabolism and energy balance. [2][3][4][5][6] Patchouli alcohol is a sesquiterpene alcohol (patchoulol), which is the characteristic component of Pogostemon cablin 7 (Fig.…”