Analysis ofAmblyomma americanummicroRNAs in response toEhrlichia chaffeensis infection and their potential role in vectorial capacity
Deepak Kumar,
Khemraj Budachetri,
Yasuko Rikihisa
et al.
Abstract:Background: MicroRNAs (miRNAs) represent a subset of small noncoding RNAs and carry tremendous potential for regulating gene expression at the post-transcriptional level. They play pivotal roles in distinct cellular mechanisms including inhibition of bacterial, parasitic, and viral infections via immune response pathways. Intriguingly, pathogens have developed strategies to manipulate the host's miRNA profile, fostering environments conducive to successful infection. Therefore, changes in an arthropod host's m… Show more
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