“…Proteomic analysis of CVF may therefore permit the identification of protein biomarkers that may play a key role in the maintenance of pregnancy and the onset of labour. Polyacrylamide gel electrophoresis of human vaginal secretions was pioneered in the early 1970s 6 and expanded to include pregnant women in the 1980s 7 . To date, however, a detailed discovery‐based study of CVF in pregnancy using proteomic technology has not been performed.…”
CVF is a complex body fluid consisting of both endogenous and environmental proteins. The putative role of some of these proteins in the human reproductive tract is discussed.
“…Proteomic analysis of CVF may therefore permit the identification of protein biomarkers that may play a key role in the maintenance of pregnancy and the onset of labour. Polyacrylamide gel electrophoresis of human vaginal secretions was pioneered in the early 1970s 6 and expanded to include pregnant women in the 1980s 7 . To date, however, a detailed discovery‐based study of CVF in pregnancy using proteomic technology has not been performed.…”
CVF is a complex body fluid consisting of both endogenous and environmental proteins. The putative role of some of these proteins in the human reproductive tract is discussed.
“…Laboratory test procedures relevant to proving the occurrence of such acts were reviewed (378). Proteins in vaginal secretions were analyzed by electrophoresis and their patterns were classified into a number of groups (379). Peptidase isoenzymes originating from several bacterial species were found to be present in vaginal swabs (380).…”
“…Previous studies identied several candidate protein markers for identifying vaginal uids. [16][17][18][19][20][21] However, the identied protein markers do not have adequate specicity for forensic identication of vaginal uids. Recently, van Steendam et al reported a method of examining vaginal uids using nano-HPLC and ESI-Q-TOF-MS 22 with digesting potential protein markers; however, other simpler methods are required for practical forensic investigation.…”
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