Analysis of Hepcidin and Interleukin-6 Levels among Transfusion-Dependent Thalassemia Patients With and Without Alloimmunization/Autoimmunization

Abstract

This circumstance, coupled with heightened IL-6, hepcidin, and a shift in the Th17 cell balance towards inflammation, initiates the formation of antibodies. 8,17,18,20 To categorize TDT patients based on antibody presence, we divided them into two groups: TDT with alloimmunization/autoimmunization and TDT without alloimmunization/autoimmunization. No studies have explored IL-6 and hepcidin levels in