Analysis of Genome Sequences of Coagulase-Negative Staphylococci Isolates from South Africa and Nigeria Highlighted Environmentally Driven Heterogeneity

Abstract

Here, we report high-quality annotated draft genomes of eight coagulase-negative staphylococci (CoNS) isolates obtained from South Africa and Nigeria. We explored the prevalence of antibiotic resistance and virulence genes, their association with mobile genetic elements. The pan-genomic analysis highlighted the environmentally driven heterogeneity of the isolates. Isolates from Nigeria had at least one gene for cadmium resistance/tolerance, these genes were not detected in isolates from South Africa. In contrast, isolates from South Africa had a tetM gene, which was not detected among the isolates from Nigeria. The observed genomic heterogeneity correlates with anthropogenic activities in the area where the isolates were collected. Moreover, the isolates used in this study possess an open pan-genome, which could easily explain the environmentally driven heterogeneity.

Phylogenomic analyses and comparative genomics of Pseudomonas syringae associated with almond (Prunus dulcis) in California

“…Such genomic variations in the architecture of the T3SS are common among (and sometimes within) the P. syringae species complex phylogroups [ 6 , 30 , 53 ]. This is attributed to the members of the species complex being apt to survive in a wide range of habitats, and such environmentally driven heterogeneity in bacteria has been described in many studies [ 6 , 54 ]. Besides P. syringae pv.…”

“…Genes conferring resistance to antibiotics/bactericides are important for the success of phytopathogens and other bacteria as they can help withstand environmental selective pressure [ 54 ]. Genome analyses revealed the presence of a gene encoding CtpV in some P. syringae pv.…”