Analysis of Fludrocortisone Acetate and Its Solid Dosage Forms by High-Performance Liquid Chromatography

Dilution of semi-solid creams: Influence of various production parameters on rheological properties and skin penetration

“…Dilutions of erythromycin and diclofenac sodium showed no differences in API content depending on the manner of manufacture. In addition, chromatography results were carefully checked for degradation products of the respective APIs, yet none were found over the period of the present study (Ast and Abdou, 1979;Chepkwony et al, 2000;Hajkova et al, 2002). Therefore, a satisfactory stability and distribution of the incorporated drugs can be assumed, independent of the production parameters, employed cream base or API.…”