Analysis of extracellular vesicle microRNA profiles reveals distinct blood and lymphatic endothelial cell origins
Marianne Pultar,
Johannes Oesterreicher,
Jaana Hartmann
et al.
Abstract:Extracellular vesicles (EVs) are crucial mediators of cell‐to‐cell communication in physiological and pathological conditions. Specifically, EVs released from the vasculature into blood were found to be quantitatively and qualitatively different in diseases compared to healthy states. However, our understanding of EVs derived from the lymphatic system is still scarce. In this study, we compared the mRNA and microRNA (miRNA) expression in blood vascular (BEC) and lymphatic (LEC) endothelial cells. After charact… Show more
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