“…To complicate the situation, a DI RNA may also be the target of RNA silencing if it produces enough dsRNA target. The DI RNAs have various sized deletions in the 2a ORF and include the GDD motif characteristic of the function of this ORF product as an RdRp (Romero et al, 1993;Pogany et al, 1995;Sandoval et al, 2008) (Figure 7.17). Graves et al, 1996) The DI RNA of BBMV is derived from, and decreases the concentration of, RNA2.…”