2022
DOI: 10.51847/ywrlcwytdc
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Analysis of effectiveness of the use of multifunctional biopolymers of chitosan and alginate in dentistry ‎

Abstract: This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-Non Commercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

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Cited by 1 publication
(2 citation statements)
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“…After administration under the conjunctiva, the highest concentration of the drug was noted after 3 hours, it disappears after 12 hours. With the disease, the barrier function weakens and the antibiotic penetrates the eye in greater quantities, nevertheless, the drug does not stay in the cornea and chamber moisture for a long time (maximum 60 minutes), but is eliminated after 2-3 hours [20]. The rapid removal of the drug from the chamber moisture is associated with its constant current and exchange [21][22][23].…”
Section: The Role Of the Blood-aqueous Barrier In The Pharmacokinetic...mentioning
confidence: 99%
See 1 more Smart Citation
“…After administration under the conjunctiva, the highest concentration of the drug was noted after 3 hours, it disappears after 12 hours. With the disease, the barrier function weakens and the antibiotic penetrates the eye in greater quantities, nevertheless, the drug does not stay in the cornea and chamber moisture for a long time (maximum 60 minutes), but is eliminated after 2-3 hours [20]. The rapid removal of the drug from the chamber moisture is associated with its constant current and exchange [21][22][23].…”
Section: The Role Of the Blood-aqueous Barrier In The Pharmacokinetic...mentioning
confidence: 99%
“…When using prolonged-acting drugs due to the slow but constant release of the drug from the enriched form with a single injection, you can get a constant concentration of the active drug in the tissues for a long time. Currently, polymer-based substances, in particular, viscoelastic, are used to increase the viscosity (prolongation) of medicinal substances [20,27,28]. Modern methods of pharmacocorrection of the permeability of the blood-aqueous barrier are few and difficult to apply in practice.…”
Section: The Role Of the Blood-aqueous Barrier In The Pharmacokinetic...mentioning
confidence: 99%