Analysis of chloramphenicol in honey by on-line pretreatment liquid chromatography–tandem mass spectrometry

Hao, Hongyuan; Hashi, Yuki; Lin, Jin‐Ming

doi:10.1016/j.cclet.2014.10.026

Cited by 36 publications

(15 citation statements)

References 11 publications

(11 reference statements)

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“…Also with the aim of removing sugars present in honey, Kawano and co‐works developed an online SPE‐LC method using a methylcellulose immobilized restricted access materials (MC‐ODS) as the first column and a C18 as the second one. With this method the authors reached 0.2 μg/kg of quantification limit, with loading pump flow rate of 1.0 mL/min.…”

Section: Selected Applications Of Multidimensional Separations In Foomentioning

confidence: 99%

An overview of multidimensional liquid phase separations in food analysis

et al. 2016

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Food safety is a priority public health concern that demands analytical methods capable to detect low concentration level of contaminants (e.g. pesticides and antibiotics) in different food matrices. Due to the high complexity of these matrices, a sample preparation step is in most cases mandatory to achieve satisfactory results being usually tedious, lengthy, and prone to the introduction of errors. For this reason, many research groups have focused efforts on the development of online systems capable to do the cleanup, concentration, and separation steps at once through multidimensional separation techniques (MDS). Among several possible setups, the most popular are the multidimensional chromatographic techniques (MDC) that consist in combining more than one mobile and/or stationary phase to provide a satisfactory separation. In the present review, we selected a variety of multidimensional separation systems used for food contaminant analysis in order to discuss the instrumentation aspects, the concept of orthogonality, column approaches used in these systems, and new materials that can be used in these columns. Selected classes of contaminants present in food matrices are introduced and discussed as example of the potential applications of multidimensional liquid phase separation techniques in food safety.

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Section: Selected Applications Of Multidimensional Separations In Foomentioning

confidence: 99%

An overview of multidimensional liquid phase separations in food analysis

et al. 2016

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“…The analytical conditions were the same as those in a previous report. 10 The method was optimized so as to maintain the column pressure below 25 MPa. Figure 4 represents an MRM chromatogram of sample A.…”

Section: Analysis Of a Royal Jelly Samplementioning

confidence: 99%

“…We previously evaluated an automated pretreatment liquid chromatography-tandem mass spectrometry (LC-MS/ MS) system with the MC-ODS column for the analysis of chloramphenicol (CAP) in honey. 10 Sugars in honey were also sufficiently removed, and quantitative analysis was successful.…”

Section: Introductionmentioning

confidence: 99%

Quantitative Analysis of Chloramphenicol in Royal Jelly by Column-switching LC-MS/MS Using a Pretreatment Column with a Higher-pressure Capability

2015

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“…A variety of studies has revealed that glycoproteins can be used as biomarkers for many diseases . MS is a powerful tool for analyzing protein glycosylation, however, the direct determination of glycoproteins with MS still presents great challenge due to their low abundance in biosamples and poor ionization efficiency in MS analysis . For this goal, various purification and enrichment processes are employed prior to MS analysis.…”

Section: Introductionmentioning

confidence: 99%

Cobalt Phthalocyanine Tetracarboxylic Acid Functionalized Polymer Monolith for Selective Enrichment of Glycopeptides and Glycans

et al. 2018

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In this study, poly(glycidyl methacrylate-ethyleneglycol dimethacrylate) monolith functionalized with cobalt phthalocyanine tetracarboxylic acid is prepared. The polymer monolithic material is used for glycopeptides enrichment coupled with MALDI-TOF MS. By taking advantage of cobalt phthalocyanine including hydrogen bonds between isoindole subunits of phthalocyanine and glycans, coordination interaction between cobalt and glycopeptides, the monolithic material is successfully applied to the enrichment of glycopeptides efficiently and selectively. With IgG and horse radish peroxidase as the model glycoproteins, 28 and 17 glycopeptides could be identified respectively after enrichment with the monolith, only four and three glycopeptides could be obtained for direct analysis. The monolith is also employed to the digests mixture of BSA and IgG (50:1, m/m), indicating the high enrichment selectivity of glycopeptides even in the presence of a large interference ratio. The detection limit is determined to be 6.7 fmol, implying that the present method had great potential for trace sample analysis. In addition, the monolith was successfully applied to the enrichment of N-linked glycans in human serum samples, demonstrating its great potential for the analysis of glycoproteins.

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Analysis of chloramphenicol in honey by on-line pretreatment liquid chromatography–tandem mass spectrometry

Cited by 36 publications

References 11 publications

An overview of multidimensional liquid phase separations in food analysis

An overview of multidimensional liquid phase separations in food analysis

Quantitative Analysis of Chloramphenicol in Royal Jelly by Column-switching LC-MS/MS Using a Pretreatment Column with a Higher-pressure Capability

Cobalt Phthalocyanine Tetracarboxylic Acid Functionalized Polymer Monolith for Selective Enrichment of Glycopeptides and Glycans

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