Analysis of Chaulmoogra Oils. III. Hydnocarpus Wightiana Oil

Abstract

Since this acid was obtained only 70.5% pure we can determine its constants only from the curves made with the other pure homologs. These probable constants are shown in Tables II and III. Aleprolic Acid.-Fraction 49W, 1, Table I, clearly indicates the presence of this very low homolog of chaulmoogric acid. The boiling point of ethyl aleprolate should be 70°at 10 mm.; being impure it boiled slightly lower.The homolog between ethyl aleprestate and ethyl aleprolate should boil at 96°at 10 mm.It is probably present but our final fractions were too small to attempt further fractionation to prove its presence.An optically inactive unsaturated acid with one double bond must be present in fraction 50W, 2 to account for the iodine number found. There may also be present a saturated acid of low molecular weight.For purposes of comparison the constants of the other known optically active acids and their ethyl esters are included in Tables II and III.

Stereochemical evidence of dual chemoreceptors for an achiral sex pheromone in Lepidoptera

“…(±)-9-(Cyclopent-2-en-l-yl)nonyl Acetate (9). The crude tetrahydropyranyl ether 8 was dissolved in acetic acid (15 mL), acetyl chloride (1 mL) was added, and the solution was warmed on a steam bath overnight.…”

The Cyclopentenyl Fatty Acids

“…The classical method for the isolation of the various cyclopentenyl fatty acids, on a preparative scale, involves fractional distillation of the methyl or ethyl esters derived from the total fatty acids of seed oils and subsequent fractional crystallization of the 'free' fatty acids from acetone [12,13,15,16]. This procedure permits oleic acid to be eliminated, but palmitic acid crystallizes with the cyclopentenyl fatty acids [2].…”

La investigación científica del Dr. José Gregorio Hernández Cisneros y su impacto en el desarrollo de la ciencia venezolana. El tratamiento de la tuberculosis pulmonar con aceite de chaulmoogra

“…A partir de los frutos de la chaulmoogra, un árbol de nombre científico Hydnocarpus wightianus, género Hydnocarpus, familia Flacourtiaceae (a veces ubicada como Achariaceae) (Figura 1a), se obtiene un aceite esencial de uso extendido en la medicina tradicional de la India (Ayurveda) y China (18), especialmente para el tratamiento de diversas enfermedades de la piel (19). Los componentes esenciales del aceite de la chaulmoogra (20), que se conocen desde por lo menos 1904 (21), tienen efectos medicinales que se atribuyen principalmente a la presencia de ácidos grasos bioactivos como el ácido chaulmoogrico y el ácido hidnocárpico (22,23). Este aceite esencial obtenido a partir de las semillas de la chaulmoogra (Figura 1b), es utilizado como un agente pigmentador de la piel, y posee la capacidad de reducir lesiones cutáneas y el enrojecimiento causado por el eritema.…”