Kinematic and force trajectories are often normalized in time, with mean and variance summary statistic trajectories reported. It has been shown elsewhere, for simple one-factor experiments, that statistical testing can be conducted directly on those summary statistic trajectories using Random Field Theory (RFT). This technical note describes how RFT extends to two-factor designs, and how bizarre "nonphasic interactions" can occur in multi-factor experiments. We reanalyzed a public dataset detailing stance phase knee flexion during walking in (a) patellofemoral pain vs. controls, and (b) females vs. males using both a full model (with interaction e↵ect) and a main-e↵ects-only model. In both models the main e↵ect of PAIN failed to reach significance at ↵=0.05. The main e↵ect of GENDER reached significance over 5-40% stance (p=0.0005), but only for the full model. The interaction e↵ect (in the full model) reached significance over 0-15% of stance (p=0.030), and resulted from greater flexion in females but decreased flexion in males in PFP vs. controls. Thus there was a non-phasic interaction, in which a non-significant interaction (over 20-40% stance) suppressed the main e↵ect of GENDER. Similarly, if we had only analyzed 20-40% stance, we would have committed Type II error by failing to reject the null PAIN-GENDER interaction hypothesis. The possible presence of non-phasic interactions implies that trajectory analyses must be conducted at the whole-trajectory level, because a failure to do so will generally miss non-phasic interactions if present.