Significant changes in the strategic goals of the construction sector at the global level have been visible in recent years. By implementing the fundamental principles of sustainable development and circular economy, the modern construction industry tries to contribute to a healthier environment by reducing CO2 emissions, minimizing waste landfills, and preserving non-renewable natural resources. The possibilities of reusing prefabricated concrete elements of existing buildings instead of their traditional recycling on a material level or disposing of them in landfills are analyzed in this paper. Special attention in the research was placed on the carbonation of prefabricated reinforced concrete elements of buildings, as it is one of the most frequent processes that accelerate the deterioration of RC structures. Long-term carbonation processes inevitably result in reinforcement corrosion and accompanying damage to the concrete cover, therefore some constrains for the further use of prefabricated RC building elements must be precisely defined. In this study, the potential use of prefab RC building elements was determined by calculating the depth of carbonation while taking into account the age of buildings and environmental conditions (relative air humidity, position of prefab element). Depending on the thickness of the carbonized concrete and the type and intensity of damage to the reinforcement and concrete, various variants for further use of the dismantled prefabricated RC building elements were proposed (reuse without restrictions, use in the interior of new buildings, use in less demanding facilities, reuse after application of a protective coating, replacement of the protective cover and reuse etc.).