Analysis of bioactive metabolites from <i>Azolla pinnata</i> against Dental caries

Selvi, K. Vanmathi; Aruna, S; Rajeshkumar, S.

doi:10.5958/0974-360x.2017.00332.8

Cited by 4 publications

(2 citation statements)

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“…Alkaloids, phenolic compounds, flavonoids, saponins, and tannins have been extracted from ferns Azolla pinnata, Marsilea minuta, and Salvinia molesta [107,108]. The former exhibited antibacterial [109] and antidiabetes properties [110]. Alkaloids, steroids, tannins, flavonoids, terpenoids, cardiac glycosides, phenolic compounds, and terpenoids have been reported from the crude extract of Cyclosorous interruptus [111].…”

Section: Pteridophytementioning

confidence: 99%

Review POTENT PHARMACEUTICAL PRODUCTS FROM AQUATIC PLANTS – REVIEW

Saxena¹,

Singh²,

Kumar³

et al. 2021

Asian J Pharm Clin Res

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Several biologically active secondary metabolites from aquatic plants have been extracted and identified using modern instrumental BioTechniques and used in various ways as flavors, food, additives, coloring agents, nutraceuticals, cosmetics, and also as unique source of pharma industries for the discovery or development of new drugs. From algae to aquatic macrophytes belonging to various categories, aquatic plants produce a variety of compounds such as polyketides, peptides, alkaloids, flavonoids, phenolic compounds, terpenes, steroids, quinones, tannins, coumarins, and essential oils commercially involving in antibiotic, antiviral, antioxidant, antifouling, anti-inflammatory, anticancer, cytotoxic, and antimitotic activities; thus making them a rich source of medicinal compounds. Moreover, they are comprehensively used in human therapy, veterinary, agriculture, scientific research, and in countless areas. Importantly these chemicals are exercised for developing new antimicrobial and cancer drugs. Furthermore, antioxidant molecules in aquatic plants and seaweeds have recently been acknowledged. This review contains a consolidated contemporary document consisting of entire knowledge available on pharmaceutical products of aquatic plants and highlights major differences among secondary metabolites found in aquatic (algae) and terrestrial plants.

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Section: Pteridophytementioning

confidence: 99%

Review POTENT PHARMACEUTICAL PRODUCTS FROM AQUATIC PLANTS – REVIEW

Saxena¹,

Singh²,

Kumar³

et al. 2021

Asian J Pharm Clin Res

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“…Dental caries is the most common multifactorial oral disease in the world and it increasing in the developing countries 1 . Dental caries has three major factor which are bacteria, host, and diet related, but the cariogenic bacteria (S. mutans) has the major role to forms biofilm that could lead to dental caries and tooth loss 2,3 . Caries among children has negative effects such as disruption in their growth and development, emotional, and cognitive development 4 .…”

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confidence: 99%

Quantification molecular weight of human beta defensin-2 and human beta defensin-3 from saliva of caries patient

Indrawati¹,

Diyatri²,

Rezkita³

et al. 2020

Rese. Jour. of Pharm. and Technol.

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Background: Dental caries is the most common multifactorial disease in the world. In saliva of caries patients, occur an increase in innate immunity, such as human beta defensin-2 (HBD-3) and human beta defensin-2 (HBD-3). Research on quantification the molecular weight of HBD-2 and HBD-3 in saliva of caries patients has not done yet. Objective: Determine the molecular weight from HBD-2 and HBD-3 from saliva of caries patients using the Western Blot method. Method: This study was approved by the Health Research Ethical Clearance Commission of Faculty of Dental Medicine Airlangga University No.156/HRECC.FODM/IV/2019. After every individual agreed, saliva sample from 16 children with caries and caries-free in the Dental Hospital Airlangga University was collected in June to July 2019. Male/female aged 9-12 years and DMF-t > 5, taken 5 ml of saliva between 8-10 o'clock, passive-drool method without stimulation. Salivary samples were centrifuged for 20 minutes, 4ºC, with 10.000 rpm. Total protein was calculated using bicinchoninic acid (BCA) Assays before loading into Sodium Dodecyl Sulfate PolyAcrilamide Gel Electrophoresis (SDS-PAGE) to evaluate protein separation based on molecular weight. Furthermore, Western Blot is performed to ensure the protein that appears is HBD-2 and HBD-3 specific protein using primary and secondary antibodies. Results: THE molecular weight of HBD-2 and HBD-3 in the saliva of caries patients is 43 kDa, while the salivary free-caries band in the gel is unreadable, thus the molecular weight cannot be determined. Conclusion: The molecular weight of HBD-2 and HBD-3 in the saliva of caries patients calculated using the Western Blot method was 43 kDa.

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