Analysis of binding and authentic virus-neutralizing activities of immune sera induced by various monkeypox virus antigens
Shuo Song,
Zuning Ren,
Jiayin Chen
et al.
Abstract:Monkeypox cases continue to increase globally, and there is an urgent need to develop a highly effective vaccine against monkeypox. This study investigated the binding and authentic-virus neutralizing activities of sera from mice immunized with EEV (extracellularly enveloped viruses) antigens B6R and A35R, and IMV (intrinsic material viruses) antigens M1R, A29L, E8L, and H3L against monkeypox virus.The results showed that immunizations of A35R and E8L could only induce lower titers of binding antibodies, in co… Show more
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