Analysis of Antithyroid Antibodies and Thyroid Hormones in Patients With Sjogren's Syndrome.

Abstract

BACKGROUNDOther autoimmune diseases are common in patients with immune-mediated thyroid disorders. In patients with Sjogren's Syndrome the frequency of autoimmune thyroiditis and thyroid hormone dysfunction, as well as its association with the clinical and laboratory manifestations of the disease, need to be better studied. The objective was to evaluate the frequency and association of the presence of antithyroid antibodies and thyroid hormone dysfunction with the clinical and laboratory manifestations of SS. MATERIALS AND METHODSRetrospective observational study that included 174 patients with SS diseases according to the classification criteria ACR / EULAR 2016, attended from January 2000 to July 2017. Data were analyzed by SPSS 18.0 using chi-square (x2) for qualitative variables and Student t test for quantitative variables, with significance at p ≤ 0.05. The measure of association used was Prevalence Ratio (PR) with Confidence Interval (95% CI).