Analysis of Antimicrobial potential of Marine red algae; Centroceras clavulatum (C. agardh) Montagne against selected strains of human pathogens

Abstract

Finding novel antimicrobial components has achieved a global research focus as the contaminating and pathogenic microbes develop resistance against standard drugs. Current study encompasses Agar well diffusion mediated Antimicrobial (Antibacterial and Antifungal) analysis using methanol extract of marine red algae Centroceras clavulatum (C. agardh) Montagne collected from coasts of Kannur District, Kerala. Tests have performed against 5 pathogenic bacteria such as Bacillus aeruginosa, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae and 5 strains of pathogenic fungi such as Candida albicans, Candida auris, Candida pelliculosa, Candida parapsilosis, and Candida tropicalis using various concentrations of sample. When compared to the colony inhibition by standard (Chloramphenicol and Fluconazole) (10µl), 25 µl concentration of sample has effectively inhibited most of the tested strains. The study suggests Centroceras clavulatum (C.Agardh) Montagne as potential seaweed to be used for isolating various antimicrobial components.