Analysis of Alu Insertion Polymorphism in South Morocco (Souss): Use of Markers in Forensic Science

Abstract

The aim of the present study is the assessment of the utility of Alu insertions in forensic DNA typing within the South Moroccan population. We report on a comprehensive study of seven loci of interest due to the insertion or the deletion of human-specific Alu fragments. The study was carried out on 215 unrelated healthy individuals, including five Souss Berber groups and one Saharawi. The accurate genotype frequency data and other genetic parameters of forensic interest were obtained. The frequencies of the Alu insertion in the total sample population were found to be 0.176 (ACE), 0.455 (TPA25), 0.196 (PV92), 0.697 (APO), 0.267 (FXIIIB), 0.373 (B65) and 0.804 (HS 3.23). The power of discrimination ranged from 0.4540 for ACE to 0.6223 for TPA25. The power of exclusion for these seven loci ranged from 0.1240 to 0.1865. The combined discrimination power and the joint power of exclusion were respectively 0.9959 and 0.6910. The results indicated that the application of Alu insertion polymorphism will assist in forensic identification and paternity testing that is performed by current STR technology.

The Position of Forensic DNA Database in Criminal Investigation: Understanding the Utilization in Africa, Particularly Nigeria a Review

“…In one of the cities in Nigeria on June 05, 2020, a 22-year-old lady was found lying half-naked in a pool of blood at the quiet nearby church where she went to study [40][41][42][43][44][45][46][47][48][49][50][51][52][53]. The church security guard was the first to find out about the situation and a report was made.…”

Genetic characterization of the Berber‐speaking population of Souss (Morocco) based on autosomal STRs

“…However, despite its historical relevance, the genetic diversity of the Souss population has not been sufficiently studied. The only studies carried out in the region have focused on mtDNA sequences, ABO polymorphism, Alu insertion, and HLA polymorphism (Brakez et al, 2001;Chadli et al, 2007Chadli et al, , 2009Izaabel et al, 1998).…”