“…It is important to question the appropriateness of the current recommendation 7 to discontinue infusions 12 h after admixture. There are several benefits associated with letting these infusions run for longer periods of time; replacing intravenous infusions every 12 h is not itself without risks and cost, more frequent handling of couplings and catheters provides more opportunities for contamination and the risk of dosage errors ought to be related to the frequency with which new solutions are mixed, especially if this must be done outside daytime working hours.…”