Analysis and optimization of enantioselective extraction in a multi-product environment with a multistage equilibrium model

3,3′‐diaryl‐BINOL phosphoric acids as enantioselective extractants of benzylic primary amines

“…PA1 shows the absorption bands as described in the literature (1474, 1462, 1427 ). 47 Upon titration with (R)-or (S)-PGL in a monophasic system of water-saturated dichloromethane and PA1 kept at c 5 1.0 mM, an additional band appears at 1098 cm 21 . Ramirez et al 48 reported the appearance of bands between 1070 and 1080 cm 21 of the phosphates formed by complexation of phosphodiesters and primary amines, which can be assigned to the stretching vibrations of the phosphoryl bond of the phosphate.…”

Reaction kinetics in reactive extraction for chiral separation of α-cyclohexyl-mandelic acid enantiomers with hydroxypropyl-β-cyclodextrin

“…At present, the studies on chiral extraction mainly focus on an extraction equilibrium (Koska and Haynes, 2001;Schuur et al, 2008b;Steensma et al, 2006a, b;Viegas et al, 2007a, b;Pickering and Chaudhuri, 1997). Equilibrium modeling can be used not only for the design of theoretical separations (Steensma et al, 2007a), but also successfully for developing fractional extraction processes (Schuur et al, 2009(Schuur et al, , 2010. The studies on the kinetics of extraction of metal ion and achiral compounds have been reported (Wasewar et al, 2002;Nishiki et al, 1998;Kaczmarski et al, 2002), but little study has been carried out concerning the chiral extraction.…”

Kinetics study on the reactive extraction of homophenylalanine enantiomers with BINAP-copper complex

“…Many researchers have attempted to separate the optically active compounds by chiral solvent extraction in recent years (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26). However, limited information concerning kinetics of reactive extraction is available (27).…”