Analysis and Management of Abnormal Cases by Multiple Intake of Korean Health Functional Foods

Kang, Kwonsoo; Lee, Kyuwon; Jung, Seok-Kyu; Kang, Daejin; Ko, Kwang Suk

doi:10.3746/jkfn.2020.49.5.511

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…Notably, Garcinia cambogia extract and green tea extract were among the top five most frequently reported ingredients in dietary supplements. An in vitro study observed liver toxicity in response to combined Garcinia cambogia extract and green tea extract, as determined by an AST/ALT activity test 19 . There have been several case reports and case-series studies of liver injury following the use of Garcinia cambogia extract for weight loss in the US, Asia, and Europe 4 .…”

Section: Discussionmentioning

confidence: 99%

Association between weight loss agents and elevated liver enzymes: a population-based cross-sectional study

Kim,

Kang,

Kim

et al. 2023

Sci Rep

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The widespread use of body weight control agents might be related to liver enzyme elevation, but this potential association has only been documented in a few case reports. This study aimed to investigate the associations between weight loss agents and elevated liver enzymes at the population-level. We conducted a cross-sectional study using Korea National Health and Nutrition Examination Survey (KNHANES) data from 2013 to 2019. This study included 36,259 participants over 20 years of age who completed the questionnaire and had no history of hepatitis, cancer, or renal failure. In these participants, we analyzed associations between weight loss agents and elevated liver enzymes by constructing multiple logistic regression models with adjustment for confounding factors and stratified by sex, age, and body mass index. The use of weight loss agents related to liver enzyme elevation in men (adjusted odds ratio (aOR): 1.36, 95% confidence interval (CI): 1.08–1.71) and participants aged less than 40 years (aOR: 1.44, 95% CI: 1.12–1.87). Using more types of weight loss agents was associated with liver enzyme elevation (aOR: 1.31, 95% CI: 1.03–1.67 for 1 weight loss agent, aOR: 1.93, 95% CI: 0.93–3.99 for ≥ 2 weight loss agents). Elevated liver enzymes were associated with the use of traditional medicines (aOR: 1.96, 95% CI: 1.14–3.34) and dietary supplements (aOR: 1.33, 95% CI: 1.02–1.72) in men. We observed an association between weight loss agents and liver enzyme elevation in men, particularly for traditional herbal medicines and dietary supplements. To confirm the observed associations, studies higher on the evidence hierarchy are needed.

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Section: Discussionmentioning

confidence: 99%

Association between weight loss agents and elevated liver enzymes: a population-based cross-sectional study

Kim,

Kang,

Kim

et al. 2023

Sci Rep

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Antioxidant Activity of Beef Tteokgalbi Added with Raspberry and Shiitake Mushroom Powder

Kang¹,

Kim²,

Kim³

et al. 2020

Resour Sci Res

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The aim of this study was to investigate the quality properties (cooking yield, color, and sensory evaluation) and antioxidant activity (total polyphenol contents, total flavonoid contents, DPPH free radical scavenging activity, and ferric acid reducing antioxidant power) of tteokgalbi formulated with various levels of raspberry and shiitake mushroom powder. Cooking yield significantly increased with increasing raspberry and shiitake mushroom powder (p<0.05). After cooked lightness and redness of RL3 were significantly higher than control (p<0.05). In sensory evaluation, RL2 received high praise in color, texture, overall acceptability than control. Total polyphenol and flavonoid contents of RL2 and RL3 were significantly higher than control (p<0.05). DPPH free radical scavenging activity of raspberry and shiitake mushroom powder treated samples were significantly higher than control (p<0.05). Ferric acid reducing antioxidant power significantly increased with increasing raspberry and shiitake mushroom powder (p<0.05). Thus, these results were shown RL2 sample is suitable for manufacturing tteokgalbi.

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We Are Not Informed Enough

2021

Food Suppl Biomater Health

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Analysis and Management of Abnormal Cases by Multiple Intake of Korean Health Functional Foods

Cited by 3 publications

References 9 publications

Association between weight loss agents and elevated liver enzymes: a population-based cross-sectional study

Association between weight loss agents and elevated liver enzymes: a population-based cross-sectional study

Antioxidant Activity of Beef Tteokgalbi Added with Raspberry and Shiitake Mushroom Powder

We Are Not Informed Enough

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