Analyse des discordances de groupes sanguins ABO RH au laboratoire de QBD du centre national de transfusion sanguine d’Abidjan

Dembelé, Bamory; Siransy-Bogui, L.; Diane, Kapche; Adiko, A.C.; Kouassi, F.P.; Alassani, F.; Konate, S.

doi:10.1016/j.tracli.2012.08.076

Cited by 2 publications

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“…Paucigeste (2 or 3 children) represented 51.8% of the sampling. This result agrees with that of Mr. Konaré in Mali, who reported in his study a preponderance of paucigest with a rate of 56.7% [8] (Table 2).…”

Section: Discussionsupporting

confidence: 93%

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Management of the Prevention of the Rhesus Alloimmunization: Case of the Mother-Child Hospital Dominique Ouattara of Bingerville/Ivory Coast/West Africa

Ecra,

Olou,

Konan

2023

OJOG

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Introduction: Perinatal mortality linked to fetal anemia of red cell alloimmunization in Côte d'Ivoire as in many developing countries can be explained by a lack of knowledge of Rhesus D feto-maternal alloimmunization, hence the obvious importance of carrying out a study on the problem of prevention of alloimmunization in rhesus negative births. This study takes stock of the management of this pathology in a reference hospital. Results and Discussion: Rh-negative mothers account for 6% of births, 42.7% (70/164) of women had a history of risk, about 61% of women had not had proper prophylaxis during previous pregnancies; and as many had not had follow-up of the coombs test during the current pregnancy; only 4.9% of patients had systematic prophylaxis with anti D serum at 28 weeks of pregnancy. This low rate of prevention is related to the financial difficulties of the patients, but also to a lack of knowledge of the pathology by the nursing staff. Conclusion: Good management of rhesus negative women during their pregnancy allows their incompatible child to benefit from all current treatments ensuring a healthy birth. It is therefore important for medical personnel to know how to deal with this rare disease in a small proportion of pregnant women.

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Section: Discussionsupporting

confidence: 93%

“…Very few data on feto-maternal anti-D alloimmunization in Côte d'Ivoire are available in the literature. However, the frequency of Rhesus negative individuals in the Ivorian population was evaluated at 14.2% of whole patients with negative rhesus with a female predominance, suggesting a risk of feto-maternal alloimmunization [8].…”

Section: Introductionmentioning

confidence: 99%

Management of the Prevention of the Rhesus Alloimmunization: Case of the Mother-Child Hospital Dominique Ouattara of Bingerville/Ivory Coast/West Africa

Ecra,

Olou,

Konan

2023

OJOG

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“…Our results are close to those found by Khachaa et al who reported that alloimmunization was greater in polytransfused patients who received more than two bags of packed red blood cells [19]. They are different from those found on the one hand by Baglo et al [12] and secondly by Dembélé et al [20] who respectively reported 15 transfusions and more than 15 transfusions.…”

Section: Discussionsupporting

confidence: 78%

“…On the other hand, age, sex, and the various pathologies from which polytransfused patients suffered were not risk factors for developing alloimmunization. Like most similar studies, age and sex were not associated with the appearance of antierythrocyte alloantibodies but rather with the number of transfusions received as in our case [1,20]. However, the size of our study population could be related to the non-correlation found.…”

Section: Discussioncontrasting

confidence: 42%

Evaluation of the prevalence of anti-erythrocyte alloimmunization in 100 polytransfused patients in Lomé, Togo

S Hounogbé,

Magnang,

L Nadjir

et al. 2023

Int J Blood Transfus Immunohematol

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Aims: Red blood cells transfusion exposes recipients to a risk of immunization. The phenotyping of red blood cells and the search for irregular erythrocyte antibodies ensure immuno-hematological safety of the transfused patients. In Togo, these tests are not systematic in transfusion. The aim of the study was to determine the rate of immunization against erythrocyte antigens in polytransfused patients in Lomé. Methods: The search for irregular agglutinins was carried out by the indirect antiglobulin test in gel-filtration in 100 polytransfused patients selected at National Center for Research and Care of Sickle Cells disease and in the care units of Campus Teaching Hospital of Lomé in Togo, from October 1, 2021 to April 30, 2022. Results: The prevalence of alloimmunization was 27% with a total of 13 different alloantibodies identified. The most represented were anti-K (18.52%), anti-E (14.81%), anti-C (11.11%), anti-Jka (11.11%), and anti-M (11.11%). Alloantibodies were more frequent in A+ blood group patients and those who received more than 4 bags of packed red blood cells. There was no link between age, sex, and the pathologies involved on one hand, and the occurrence of anti-erythrocyte alloimmunization on the other. Conclusion: The rate of immunization against erythrocyte antigens is very high in polytransfused patients in Lomé. Systematic implementation of red blood cells phenotyping and irregular erythrocyte antibodies research before and after transfusion should ensure better immunological transfusion safety in Togo.

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Analyse des discordances de groupes sanguins ABO RH au laboratoire de QBD du centre national de transfusion sanguine d’Abidjan

Cited by 2 publications

References 0 publications

Management of the Prevention of the Rhesus Alloimmunization: Case of the Mother-Child Hospital Dominique Ouattara of Bingerville/Ivory Coast/West Africa

Management of the Prevention of the Rhesus Alloimmunization: Case of the Mother-Child Hospital Dominique Ouattara of Bingerville/Ivory Coast/West Africa

Evaluation of the prevalence of anti-erythrocyte alloimmunization in 100 polytransfused patients in Lomé, Togo

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