Analogs of Ephedrine and Adrenaline Containing the Morpholine Nucleus and Some of Their Esters

The Reactions of Unsaturated Ketones and Derivatives with Amino Compounds. Amino Ketones.

“…The postulated intermediate phenylhydrazones of the «, ß-unsaturated ketones were not isolated, however. Several investigators have reduced certain -amino and ß-amino ketones to the corresponding amino alcohols, using sodium amalgam (44,62,77,79), aluminum isopropoxide (21), or various catalytic methods (2, 67,102) in attempts to produce pharmacologically active substances. Hartung (58,59) has discussed the pressor activity of certain -amino ketones and alcohols in two review articles.…”

The Reactions of Monomeric Styrenes.

“…Other AT, .V-dialkylphenylethanolamines generally have been prepared by the same methods previously described for the less highly substituted compounds. (t-C,H,0),Al 69 (272) Hi + Pd 87.5 (630) , + Pd In table 33 are listed those , .V-dialkylphenylethanolamines which have been prepared by the reduction of the corresponding w^AjA-dialkylamino)acetophenone.…”

The Interaction of Certain a-(4-Morpholinyl)alkyl Aryl Ketones with Potassium Cyanide and Ammonium Carbonate

“…Thus no information was given to indicate whether failure to obtain the desired hydantoins was due to unreactivity of these ketones, inability to isolate the hydantoins, or to formation of other, non-hydantoin products. 4 Gabriel (5) so named a product which is better termed 5-phenyl-5-[l-(5-phenylhydantyl) ] hydantoin. product formed from IX, for IX, when allowed to stand in alkaline solution exposed to air, is slowly converted into X.…”