Analixity: An open source, low-cost analysis system for the elevated plus maze test, based on computer vision techniques

González-Gaspar, Patricia; Macías-Carballo, Monserrat; Cadena-Mejía, Teresa; Landa-Jiménez, Miguel A.; Montes-Gonzalez, Fernando; López‐Meraz, María Leonor; Beltran-Parrazal, Luis; Morgado-Valle, Consuelo

doi:10.1016/j.beproc.2021.104539

Cited by 3 publications

(4 citation statements)

References 15 publications

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“…The GST assessed walking behaviour 45 . GST was performed in a black plexiglass box measuring 40 × 40 × 40 cm (length × width × height) equipped with the video‐based Any‐Maze system 46 . The GST arena was divided into 25 equal squares, and animals were placed in the corner squares and allowed to move freely.…”

Section: Methodsmentioning

confidence: 99%

“…45 GST was performed in a black plexiglass box measuring 40 Â 40 Â 40 cm (length Â width Â height) equipped with the video-based Any-Maze system. 46 The GST arena was divided into 25 equal squares, and animals were placed in the corner squares and allowed to move freely. A Logitech C310 HD Webcam (Logitech) with a built-in rear camera was used to record rat videos for gait analysis.…”

Section: Gait Scores Setup and Video Recordingmentioning

confidence: 99%

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Metabolomic modelling and neuroprotective effects of carvacrol against acrylamide toxicity in rat's brain and sciatic nerve

Durmus,

Burak,

Goktug

et al. 2024

Clin Exp Pharma Physio

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The study aimed to investigate the harmful effects of acrylamide (AA), which forms in carbohydrate‐rich foods at temperatures above 120°C, on the central and peripheral nervous systems and to evaluate the potential neuroprotective effects of carvacrol (CRV). Male Wistar Albino rats were subjected to AA (40 mg/kg/bw/day) and CRV (50 mg/kg/bw/day) for 15 days. Following the last administration, evaluations revealed disrupted gait, heightened thermal sensitivity and altered paw withdrawal thresholds in AA‐exposed rats. Notably, AA reduced glutathione (GSH) and raised malondialdehyde (MDA) levels in both brain and sciatic nerve tissues. AA raised nuclear factor erythroid 2‐related factor 2 (Nrf2), caspase 3 and nuclear factor κB (NF‐κB) gene expressions while decreasing NR4A2. CRV co‐administration mitigated gait abnormalities, elevated GSH levels and lowered MDA levels in both tissues. CRV also modulated gene expression, reducing Nrf2 and NF‐κB while increasing NR4A2. Histopathological signs of AA‐induced neurodegeneration and elevated glial fibrillary acidic protein levels observed in brain and sciatic nerve tissues were rectified with simultaneous administration of CRV, thereby demonstrating neuroprotective efficacy in both regions. This study is pioneering in demonstrating CRV's neuroprotective potential against AA‐induced neurotoxicity in both central and peripheral nervous systems, effectively addressing limitations in the literature. In conclusion, the study revealed AA‐induced neurodegeneration in the brain and sciatic nerve, with CRV significantly mitigating this neurotoxicity. This novel research underscores CRV's promise as a neuroprotective agent against AA‐induced adverse effects in both the central and peripheral nervous systems.

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Section: Methodsmentioning

confidence: 99%

Section: Gait Scores Setup and Video Recordingmentioning

confidence: 99%

Metabolomic modelling and neuroprotective effects of carvacrol against acrylamide toxicity in rat's brain and sciatic nerve

Durmus,

Burak,

Goktug

et al. 2024

Clin Exp Pharma Physio

View full text Add to dashboard Cite

show abstract

“…Both to avoid the appearance of reflections, but also to facilitate the subsequent various image processing algorithms. Lambert's law states that the effect of diffuse reflection is related to the orientation of the surface with respect to the light source, that is: (5) Where is the brightness of a point on a visible surface caused by diffuse reflection.…”

Section: Table 1 Classification Of Common Light Sourcesmentioning

confidence: 99%

“…The spatial environment has a serious impact on the results of computer testing, which not only causes economic benefit loss to the relevant enterprises, but also seriously affects the competition of the computer industry in the international arena [4]. At present, most of the computer testing relies on manual to detect and identify the fault point, however, the manual detection method has limited detection accuracy, detection speed is not high, the test results are easy to be affected by the subjective factors of manual, high labor costs [5]. Thus making the computer in operation there are potential quality hazards, which directly leads to the inefficiency of machine vision inspection, reducing the competitiveness of the computer industry, and ultimately may face the end of being eliminated from the market [6].…”

Section: Introductionmentioning

confidence: 99%

Strategies for improving the detection accuracy of computerized machine vision considering spatial applications

Piao,

Song

2024

3C TIC

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In this paper, strategies in image preprocessing, hardware composition and detection methods are considered to improve computerized machine vision detection accuracy. First, image preprocessing and image enhancement are performed to improve the quality of the input image. Second, the hardware composition of the computer vision online inspection system is optimized by focusing on the light source selection and the performance of the image acquisition card in spatial applications. Combined with spatial application calculations, methods such as frequency domain method and Canny operator are used in order to improve the accuracy of machine vision detection. Finally, in the same test environment, the machine vision detection requires only 400MB and the detection accuracy ranges from 85.13% to 99.42%. With these comprehensive strategies, this paper provides a comprehensive and effective approach for computerized machine vision detection in spatial applications to improve detection accuracy and meet demanding application scenarios.

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Lateral hypothalamic orexin neurons mediate electroacupuncture-induced anxiolytic effects in a rat model of post-traumatic stress disorder

Lü

Qin

Wang

et al. 2023

Brain Research Bulletin

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Analixity: An open source, low-cost analysis system for the elevated plus maze test, based on computer vision techniques

Cited by 3 publications

References 15 publications

Metabolomic modelling and neuroprotective effects of carvacrol against acrylamide toxicity in rat's brain and sciatic nerve

Metabolomic modelling and neuroprotective effects of carvacrol against acrylamide toxicity in rat's brain and sciatic nerve

Strategies for improving the detection accuracy of computerized machine vision considering spatial applications

Lateral hypothalamic orexin neurons mediate electroacupuncture-induced anxiolytic effects in a rat model of post-traumatic stress disorder

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