Análisis molecular de la resistencia a fluoroquinolonas y macrólidos en aislados de Campylobacter jejuni de humanos, bovinos y carne de ave

González-Hein, Gisela; Cordero, Ninoska; Garcı́a, Patricia; Figueroa, Guillermo

doi:10.4067/s0716-10182013000200003

Cited by 19 publications

(9 citation statements)

References 19 publications

(29 reference statements)

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“…The high percentage of C . jejuni strains with a mutation of the gyrA gene, which confers quinolone resistance, is consistent with recent studies from Chile, reporting ciprofloxacin resistance of 30–60% [ 9 , 11 – 13 ]. One study reported that most resistant strains were associated with ST-48 [ 54 ], but we did not find an association to any particular STs.…”

Section: Discussionsupporting

confidence: 91%

Genomic analysis of the diversity, antimicrobial resistance and virulence potential of clinical Campylobacter jejuni and Campylobacter coli strains from Chile

et al. 2021

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Campylobacter jejuni and Campylobacter coli are the leading cause of human gastroenteritis in the industrialized world and an emerging threat in developing countries. The incidence of campylobacteriosis in South America is greatly underestimated, mostly due to the lack of adequate diagnostic methods. Accordingly, there is limited genomic and epidemiological data from this region. In the present study, we performed a genome-wide analysis of the genetic diversity, virulence, and antimicrobial resistance of the largest collection of clinical C. jejuni and C. coli strains from Chile available to date (n = 81), collected in 2017–2019 in Santiago, Chile. This culture collection accounts for more than one third of the available genome sequences from South American clinical strains. cgMLST analysis identified high genetic diversity as well as 13 novel STs and alleles in both C. jejuni and C. coli. Pangenome and virulome analyses showed a differential distribution of virulence factors, including both plasmid and chromosomally encoded T6SSs and T4SSs. Resistome analysis predicted widespread resistance to fluoroquinolones, but low rates of erythromycin resistance. This study provides valuable genomic and epidemiological data and highlights the need for further genomic epidemiology studies in Chile and other South American countries to better understand molecular epidemiology and antimicrobial resistance of this emerging intestinal pathogen.

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Section: Discussionsupporting

confidence: 91%

Genomic analysis of the diversity, antimicrobial resistance and virulence potential of clinical Campylobacter jejuni and Campylobacter coli strains from Chile

et al. 2021

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“…isolated from retail chicken meat in Chile (González‐Hein et al . 2013; Lapierre et al . 2016) shows similar values to those that we reported here in A. butzleri and this could reflect the effect of the use of antibiotics in the poultry industry.…”

Section: Resultsmentioning

confidence: 99%

Antimicrobial resistance and virulence genes profiles of Arcobacter butzleri strains isolated from back yard chickens and retail poultry meat in Chile

Vidal-Veuthey

Jara

Santander

et al. 2020

Lett Appl Microbiol

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This research aims to investigate the presence and pathogenic potential of Arcobacter in poultry meat samples purchased in the retail market of Valdivia (South of Chile) as well as in faecal samples from backyard chickens from rural areas around this city. The isolates obtained were identified by molecular methods. Furthermore, putative virulence genes were assessed by PCR and the antimicrobial resistance was tested by phenotypic methods. Arcobacter was present in 41·6% of the samples, with the highest value in retail poultry meat (55·7%) followed by backyard production (28·0%). Arcobacter butzleri was the most prevalent species (75·6%) followed by Arcobacter skirrowii (14·8%) and Arcobacter cryaerophilus (9·6%). An 8·5% of A. butzleri strains from meat were resistant to both ciprofloxacin and tetracycline and 6·1% were resistant to erythromycin, while none was resistant to gentamycin, unlike strains from domestic chickens, which showed no resistance. Furthermore, A. butzleri strains from chicken meat presented a higher prevalence of virulence genes than strains from domestic chickens. In fact, in this last group, some genes (hecA, hecB and irgA) were completely absent. Therefore, this study provides insight on the epidemiology of Arcobacter in Chilean poultry and suggests that under traditional breeding conditions strains are, apparently, less pathogenic and drug resistant.

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“…Antimicrobial resistance is transmitted between microorganisms through the acquisition of genetic material by conjugation, transformation or transduction processes of plasmids, transposons and integrons that contribute to the incorporation of resistance genes between microorganisms of the same genus (horizontal transmission) or different genera (vertical transmission) (Becerra et al, 2009;Cires, 2002;Pérez-Cano & Robles-Contreras, 2013). In recent years, the resistance of different pathogens in foods, such as Salmonella spp., E. coli, and L. monocytogenes, has been reported (De Nes, Riboldi, Frazzon, d'Azevedo & Frazzon, 2010; Puig Peña, Espino Hernández IJFS October 2020 Volume 9 pages 394-406 (Dallal et al, 2010;Fernandez, 2011;Gonzalez-Hein, Cordero, Garcia & Figueroa, 2013;Wieczorek & Osek, 2013). Microorganisms are reservoirs of antimicrobialresistance genes which can potentially be exchanged between other pathogenic and commensal bacteria.…”

Section: Resistance To Antimicrobialsmentioning

confidence: 99%

Food, fish and campylobacteriosis

Cortés-Sánchez

2020

IJFS

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Food is a necessity of human beings, and the consumption of food is aimed at obtaining energy and nutrients necessary for the growth and proper functioning of the body. However, food can also be a vehicle for various diseases, and the causal agents can have physical, chemical or biological origin with relevance to health due to their incidence, mortality and negative consequences in the population. Bacteria are the main agents of biological origin associated with foodborne diseases. Among these microorganisms are species of the genus Campylobacter, which cause a zoonosis with one of the highest incidences globally, known as Campylobacteriosis. This document provides an overview of foodborne diseases, specifically the causal agents of Campylobacteriosis, including the different measures of control and prevention for this disease in different foods such as poultry, milk, meat, and fish, among others. It also covers the phenomenon of resistance to antimicrobials by these pathogens and the health implications to consumers. The above can generate and maintain safety practices in food production for the protection of public health in different regions around the world.

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Análisis molecular de la resistencia a fluoroquinolonas y macrólidos en aislados de Campylobacter jejuni de humanos, bovinos y carne de ave

Cited by 19 publications

References 19 publications

Genomic analysis of the diversity, antimicrobial resistance and virulence potential of clinical Campylobacter jejuni and Campylobacter coli strains from Chile

Genomic analysis of the diversity, antimicrobial resistance and virulence potential of clinical Campylobacter jejuni and Campylobacter coli strains from Chile

Antimicrobial resistance and virulence genes profiles of Arcobacter butzleri strains isolated from back yard chickens and retail poultry meat in Chile

Food, fish and campylobacteriosis

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