Análisis de la efectividad de un protocolo de antiemesis implantado en la Unidad de Oncología

Abstract

The proposed antiemetic protocol is effective for controlling vomiting in chemotherapy regimens with an HL of 1-3. For highly emetogenic regimens, the antiemetic protocol is also effective, but protection is not complete. This protocol seems less effective for controlling nausea, although this is a subjective symptom which is difficult to assess and not routinely measured in clinical trials.

Adherence to antiemetic guidelines and control of chemotherapy-induced nausea and vomiting (CINV) in a large hospital

“…Compliance here was 68% and 85%. 19,21 Our patients, whose compliance with treatment was lower (61%), had slightly less protection than these studies.…”

Incidence and management of chemotherapy-induced nausea and vomiting in women with breast cancer

“…(3) Eff ective treatment reduces morbidity and the risk of complications, and also prevents premature termination of chemotherapy. (4) All chemotherapy drugs have emetogenic potential of diff erent intensities. However, such emetogenic risk does not include nausea.…”

Integrative review of factors related to the nursing diagnosis nausea during antineoplastic chemotherapy

“…The most frequent factor related to the ND nausea while undergoing chemotherapy was being younger than 50 years old, which was reported by 14 studies 12 - 13 , 20 - 21 , 23 , 26 - 28 , 30 , 32 , 35 - 38 . Young patients more frequently reported acute and late nausea induced by antineoplastic chemotherapy than older patients in all the treatment cycles 41 , and also reported that these symptoms negatively impacted their daily lives 42 .…”

“…Another individual factor was the patient's sex. Nausea was more frequently identified among women than among men 20 - 21 , 23 , 27 , 28 , 30 , 35 - 38 . The same was observed with regard to acute nausea, which affected 48% of women compared to 18% of men, as well as for late nausea, which affected 75% of women versus 51% of men 40 .…”

“…The studies under analysis also reported that the emetogenic potential of chemotherapy agents was the most frequent related factor, which was identified in 10 studies 13 - 14 , 17 , 20 , 22 - 23 , 31 , 35 , 38 , 40 .…”