Análise dos medicamentos relaxantes musculares de ação central comercializados no Brasil na perspectiva do Cuidado ao Idoso

Júnior, Nelson Machado do Carmo; Reis, Adriano Max Moreira

doi:10.22421/1517-7130.2017v18n1p108

Espac. Saude - Rev. Saúde Pública Paraná

2017

DOI: 10.22421/1517-7130.2017v18n1p108

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Análise dos medicamentos relaxantes musculares de ação central comercializados no Brasil na perspectiva do Cuidado ao Idoso

Nelson Machado do Carmo Júnior

Adriano Max Moreira Reis

Abstract: Resumo: Objetivo: Analisar na perspectiva do idoso as evidências científicas relativas ao emprego terapêutico e a segurança de relaxantes musculares registrados no Brasil. Método: estudo de análise da oferta de medicamentos contendo fármacos do grupo M03B -Relaxantes musculares de ação central da classificação Anatômica Terapêutica Química. Verificaram-se os fármacos do grupo M03B registrados no Brasil. Pesquisaram-se as evidências científicas relativas à segurança e eficácia. Analisou-se a disponibilidade de … Show more

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Use of potentially inappropriate medications and adverse events in older outpatients with acute conditions

Viana¹,

Souza²,

Aliberti³

et al. 2022

Einstein (São Paulo)

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Objective: To examine associations between potentially inappropriate medication, use and the risk of falls, unplanned hospitalization and death in older patients receiving initial care in a geriatric day hospital due to acute conditions. Methods: Cohort study with older adults referred to a geriatric day hospital from 2014 to 2017 due to acute conditions. Patients were submitted to comprehensive geriatric assessment. Use of medications was analyzed according to Beers Criteria 2019. Outcome assessment was based on monthly follow-up telephone calls made over the course of one year. Results: In this sample, 40.6% of patients had been prescribed at least one potentially inappropriate medication, particularly proton pump inhibitors (66.5%). Over the course of follow-up, 44.7% of patients receiving potentially inappropriate medications sustained at least one fall (p=0.0043) and 70% visited the emergency department (p=0.0452). These outcomes were more common among patients using two or more of drugs. Use of potentially inappropriate medication was associated with a 64% increase in the odds of unplanned hospitalization and a two-fold increase in risk of death. Conclusion: Associations between potentially inappropriate medication use and unfavorable outcomes such as falls and unplanned hospitalizations within one year of admission to a geriatric day hospital support the application of Beers Criteria and emphasize the importance of periodic prescription review, deprescription and rational use of these drugs whenever possible.

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Use of potentially inappropriate medications and adverse events in older outpatients with acute conditions

Viana¹,

Souza²,

Aliberti³

et al. 2022

Einstein (São Paulo)

View full text Add to dashboard Cite

show abstract

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Análise dos medicamentos relaxantes musculares de ação central comercializados no Brasil na perspectiva do Cuidado ao Idoso

Cited by 1 publication

References 20 publications

Use of potentially inappropriate medications and adverse events in older outpatients with acute conditions

Use of potentially inappropriate medications and adverse events in older outpatients with acute conditions

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