Análise da adesão à terapia antineoplásica oral de pacientes atendidos na farmácia de quimioterapia de um hospital público de Mato Grosso do Sul

Roese, Fabiana Mesquita; Fontana, Eliane Moro; Pereira, Karen Carla de Brito

doi:10.22567/rep.v7i2.499

Cited by 1 publication

(2 citation statements)

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Section: Introductionmentioning

confidence: 99%

“…3 For these cases, Adjuvant Hormonal Therapy (AHT) is an important part of the endocrine treatment of breast cancer with positive hormone receptors and it is indicated the daily use of an oral pill for a period of five to ten years, the necessary time to obtain effective results. [4][5][6] The two most common medicines used in AHT are tamoxifen, which is a selective estrogen modulator, and anastrozole, which belongs to the class of Aromatase Inhibitors. The mechanism of action of both drugs is to reduce estrogen synthesis by blocking the conversion of androgens to estrogen.…”

Section: Introductionmentioning

confidence: 99%

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The role of the clinical pharmacist in guiding adjuvant hormonal therapy in patients with breast cancer

Pirolli

Brusamarello

Everton

et al. 2021

J Oncol Pharm Pract

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Breast cancer is the most prevalent type of cancer among women, affecting about 2.1 million worldwide and is responsible for the highest number of cancer-related deaths among women. Approximately 80% of breast cancers express on the surface of hormone receptor cells, such as progesterone and estrogen. In these cases, Adjuvant Hormonal Therapy (AHT) is indicated for a period of five to ten years and consists of taking a daily oral pill. The two most used drugs in AHT are tamoxifen and Aromatase Inhibitors. One of the issues most faced by individuals who are subjected to long periods of treatment is the lack of medication adherence and, consequently, therapeutic inefficiency. It is believed that the monitoring by the pharmacist can contribute to the reduction of errors inherent to the medication, making the treatment more effective and improving the patient's quality of life. The present study aimed to know the perception of patients who live with breast cancer and who do AHT in relation to the educational performance of the clinical pharmacist. This is a qualitative, descriptive and exploratory study, carried out from March to October 2020, with 15 women undergoing treatment at the oncology unit of a tertiary-care hospital in south of Brazil. The data were obtained through a semi-structured interview using an instrument composed of two parts, one referring to the characterization of the participants and the other with the guiding question of the research: "How do you perceive the role of the pharmacist in relation to the guidelines for the use of adjuvant hormonal therapy?". The method of theoretical saturation was used to perform the sample closure and the thematic analysis was used to analyze the data. The participants were between 32 and 74 years old, seven were on tamoxifen therapy and eight on anastrozole, ten were on the first year of treatment, two on the second and three on the third year. The themes that emerged were: pharmacist-patient interaction as a safety factor in hormone therapy; role of the pharmacist in the development of strategies for self-management of the patients during hormone therapy; and, challenges for the pharmacist in relation to hormone therapy through continued guidance. It was evident that the pharmacist's educational action encouraged the participants to carry out the treatment in a more confident and assertive manner according to their particularities and beliefs.

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