Analgesic nephropathy selectively affecting a unilateral non-functioning hypoplastic kidney

Analgesic use and the risk for progression of chronic kidney disease

“…In addition, PHS showed use of aspirin was associated with a possible but non‐significant increase in risk for change in kidney function in participants with cardiovascular risk factors 22. A recent report describes a case who consumed analgesics for years with nephropathy discriminately involving the unilateral non‐functioning kidney and sparing the contralateral normal one 25. All above evidence imply that pre‐existing renal disease may be important in the adverse renal effects of analgesics or longer duration of follow‐up may be needed to identify the renal risk in healthy individuals.…”