Analgesic Efficacy of Tramadol and Butorphanol in Mandibular Third Molar Surgery: A Comparative Study

Abstract

Background Butorphanol tartrate, a mixed synthetic agonistantagonist opioid analgesic has been used for management of postoperative pain in minor and major surgical procedures.14,20 Tramadol hydrochloride is a centrally acting opioid which is effectively used in postoperative pain in various minor and major surgeries. Materials and methods Twenty subjects selected randomly received butorphanol tartrate 1 mg intramuscular and 20 subjects received tramadol hydrochloride 50 mg intramuscular after the removal of mandibular third molars. Time of injection, amount of anesthetic injected, duration of surgery, adverse effects were recorded.21 Results The mean amount of LA administered in butorphanol group was 2.6450 ml and in tramadol group was 2.640 ml respectively, the mean duration for surgery was 56.75 and 53.5 minutes for butorphanol and tramadol groups respectively which was statistically not significant. Pain assessment was done with VAS which showed mean of 19.2 and 15.5 mm (p = 0.001) which was significant for butorphanol and tramadol respectively after 12 hours. The mean time for rescue medication requirement was 5.9 hours (for tramadol) and 8.4 hours (for butorphanol). Effective analgesic activity was seen by butorphanol 1 mg intramuscular then tramadol 50 mg. Conclusion Butorphanol 1 mg was more effective than tramadol 50 mg in respect to postoperative analgesia. How to cite this article Hassan SS, Ahmed A, Rai M, Kalappa TM. Analgesic Efficacy of Tramadol and Butorphanol in Mandibular Third Molar Surgery: A Comparative Study. J Contemp Dent Pract 2012;13(3):364-370.

Effectiveness of Butorphanol Intra Articular Injection in Signs and Symptoms of Internal Disorders of the Temporomandibular Joint Among Yemeni Patients in Sana'a City.

“…At 1 week, 1 month, and 3 months in the current trial, the pain score decreased in a highly statistically significant manner. This was in line with the findings of studies by Al-Kibsi et al [5] and Hassan et al [11], which found that administering butorphanol at a dose of 1 mg was more effective than tramadol at a dose of 50 mg for postoperative analgesia following the removal of third molar impaction. It was also consistent with the findings of the study by Bhumika et al [12], which came to the conclusion that efficiency and pain relief were reduced in patients with arthritis by roughly 80% in a dose-dependent, stereo-selective, antagonistreversible way [8].…”

Preemptive subcutaneous tramadol for post-operative pain in lower abdomen surgeries: A randomized double blinded placebo-control study

“…showed that butorphanol 1 mg was more effective than T 50 mg in respect to post-operative analgesia in mandibular third molar surgery. [23] Another study by deCosta Arajua et al . has noted that nimesulide and T chlorhydrate demonstrate similar preemptive analgesic effects when used in lower third molar surgeries.…”

Advances in the Use of Butorphanol Tartrate in Postoperative Analgesia after Cesarean Section

“…In painless gastrointestinal endoscopy, the use of butorphanol tartrate not only reduces the incidence of physical movement and coughing in patients, which is conducive to the smooth operation of endoscopy, but also reduces the amount of propofol used, reduces the pain of propofol injections, and reduces the incidence of adverse reactions, such as dizziness, drowsiness, and respiratory depression, and shortens the recovery time of patients [18,19] . The analgesic effect of using Butorphanol for mandibular third molar extraction is significantly better than Tramadol in the dental clinic [20] . The use of Butorphanol tartrate in painless abortion, with its longer sedative-analgesic effect, can effectively relieve the pain of postoperative uterine contractions, lower incidence of nausea and vomiting and respiratory depression, also improves the intraoperative and postoperative safety and comfort of patients [21] .…”