Analgesic efficacy of erector spinae plane block versus paravertebral block in lung surgeries—A non‐inferiority randomised controlled trial
Pedro Hilton de Andrade Filho,
Victor Egypto Pereira,
Daniel da Escossia Melo Sousa
et al.
Abstract:BackgroundPain management plays an essential role in postoperative recovery after lung surgeries. The Erector Spinae Plane Block (ESPB) is a widely used regional anaesthesia technique; however, few clinical trials have compared this block to active control in thoracic surgeries. This study evaluated the non‐inferiority of the analgesia provided by ESPB when compared to paravertebral block (PVB) in lung surgeries.MethodsRandomised, active‐controlled, blinded for patients and assessors, non‐inferiority trial. Pa… Show more
“…[ 4 ] Thus, a non-inferiority margin of 1.0 points is often selected in randomised controlled non-inferiority trials comparing the postoperative analgesic efficacy of different regional blocks. [ 5 6 ]…”
mentioning
confidence: 99%
“…In designing a randomised controlled non-inferiority trial, the non-inferiority margin is actually the effect size and is used for sample size evaluation[ 3 ] as performed in other works. [ 5 6 ]…”
“…[ 4 ] Thus, a non-inferiority margin of 1.0 points is often selected in randomised controlled non-inferiority trials comparing the postoperative analgesic efficacy of different regional blocks. [ 5 6 ]…”
mentioning
confidence: 99%
“…In designing a randomised controlled non-inferiority trial, the non-inferiority margin is actually the effect size and is used for sample size evaluation[ 3 ] as performed in other works. [ 5 6 ]…”
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