Analgesic efficacy of an ibuprofenreleasing foam dressing compared with local best practice for painful exuding wounds

Arapoglou, Vassilis; Katsenis, K; Syrigos, Konstantinos; Dimakakos, Evangelos; Zakopoulou, Niki; Gjødsbøl, Kristine; Glynn, Chris; Schäfer, Elmar; Petersen, B.; Tsoutos, D

doi:10.12968/jowc.2011.20.7.319

Cited by 37 publications

(32 citation statements)

References 21 publications

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“…It may be persistent and/or exacerbated during dressing changes. Pain can also negatively influence healing, as the painful stimulus is associated with the release of inflammatory mediators, which potentially reduce tissue repair and regeneration 16,[30][31][32] . In the present study, all patients in the two groups reported severe pain at the beginning of data collection, but the participants of the SG, who were treated with the non-adherent Ibuprofen foam dressing, showed significant pain improvement in the second week of treatment.…”

Section: Discussionmentioning

confidence: 99%

“…Regarding the CG, after the fourth consultation, the patients reported moderate pain, while SG patients reported no pain. In a study with non-adherent Ibuprofen foam dressing, the authors concluded that this it was effective in relieving pain 16 . In our study, patients treated with IFD also showed significant improvement after the first week of treatment.…”

Section: Discussionmentioning

confidence: 99%

“…The Ibuprofen foam dressing (IFD) is a non-adherent dressing, formed by foam attached to a semipermeable polyurethane film that allows Ibuprofen release into the wound by the presence of fluids or exudate. It is an innovative technology that promotes better control of the exudate, ensures a minimum risk of leakage or maceration of the skin, brings pain relief during the use time and during its exchange and promotes a humid environment [16][17][18] . This study aimed to evaluate the impact of non-adherent Ibuprofen foam dressing in pain control of patients with venous ulcers.…”

Section: Introductionmentioning

confidence: 99%

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Impact of non-adherent Ibuprofen foam dressing in the lives of patients with venous ulcers

Salomé

Ferreira

2017

Rev. Col. Bras. Cir.

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Objective : to evaluate pain in patients with lower limb venous ulcer who used non-adherent Ibuprofen foam dressing (IFD). Methods : we conducted a prospective study of patients with lower limb venous ulcers treated from April 2013 to August 2014. We used the Numerical Scale and McGill Pain Questionnaire, performing the assessments at the moment of inclusion of the patient in the study and every eight days thereafter, totaling five consultations. We divided the patients into two groups: 40 in the Study Group (SG), who were treated with IFD, and 40 in the Control Group (CG), treated with primary dressing, according to tissue type and exudate. Results : at the first consultation, patients from both groups reported intense pain. On the fifth day, SG patients reported no pain and the majority of CG reported moderate pain. Regarding the McGill Pain Questionnaire, most patients of both groups reported sensations related to sensory, affective, evaluative and miscellaneous descriptors at the beginning of data collection; after the second assessment, there was slight improvement among the patients in the SG. After the third consultation, they no longer reported the mentioned descriptors. CG patients displayed all the sensations of these descriptors until the fifth visit. Conclusion : non-adherent Ibuprofen foam dressing is effective in reducing the pain of patients with venous ulcers.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Impact of non-adherent Ibuprofen foam dressing in the lives of patients with venous ulcers

Salomé

Ferreira

2017

Rev. Col. Bras. Cir.

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“…In addition to an early onset of pain relief after application of the ibuprofen foam dressing, a reduction of pain during dressing change could be achieved. These data were affirmed by another randomized controlled trial (RCT) in 2011 [6]. Topically applied NSAIDs also may be associated with local contact allergic reactions [7].…”

Section: Analgeticsmentioning

confidence: 93%

Recent Developments in Topical Wound Therapy: Impact of Antimicrobiological Changes and Rebalancing the Wound Milieu

Erfurt‐Berge

Renner

2014

BioMed Research International

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Wound therapy improves every year by developing new wound treatment options or by advancing already existing wound materials, for example, adding self-releasing analgesic drugs or growth factors to wound dressings, or by binding and inactivating excessive proteases. Also new dressing materials based on silk fibers and enhanced methods to reduce bacterial burden, for example, cold argon plasma, might help to fasten wound healing.

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“…Topical NSAIDs seem to be the safest choice among all options for localized pain in superfi cial joints and have demonstrated effi cacy similar to oral NSAIDs, with a low incidence of adverse events (Baraf et al 2011 ). A randomized clinical trial with ibuprofen foam dressing has also shown a signifi cant pain relief in fi ve types of wound: arterial, venous, and mixed arterial-venous leg ulcers, vasculitis, and traumatic ulcers (Arapoglou et al 2011 ). Transdermal fentanyl in non-naïve patients has been used for a number of years, with improved pharmaceutical forms and dosages.…”

Section: Could Topical Administration Of Drugs Be An Option To Prevenmentioning

confidence: 99%

Pharmacological Pain Management: For Better or for Worse?

Pickering

Lussier

2015

Pain, Emotion and Cognition

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Although taking advantage of the synergistic effect of nonpharmacological and pharmacological approaches for the treatment of pain is always recommended, drugs remain the fi rst and sometimes the only line of available treatment. Analgesics as well as pain itself do have an impact on cognitive and emotional processes. The cognitive/affective central effect of analgesics prescribed for chronic pain treatment is well documented in the literature, but the causal relationship of pain to cognitive and emotional disorders remains to be explored. In order to provide satisfactory pain alleviation, analgesic treatment in frail patients and in patients with preexisting cognitive/affective impairment is particularly diffi cult. Considering the large array of adverse events of orally administered analgesics, topical analgesics may be an interesting option for pain treatment. Non-pharmacological therapies should always be included in a comprehensive pain management plan.

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Analgesic efficacy of an ibuprofenreleasing foam dressing compared with local best practice for painful exuding wounds

Cited by 37 publications

References 21 publications

Impact of non-adherent Ibuprofen foam dressing in the lives of patients with venous ulcers

Impact of non-adherent Ibuprofen foam dressing in the lives of patients with venous ulcers

Recent Developments in Topical Wound Therapy: Impact of Antimicrobiological Changes and Rebalancing the Wound Milieu

Pharmacological Pain Management: For Better or for Worse?

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