Analgesic effect of Salmon calcitonin in osteoporotic vertebral fractures: A double-blind placebo-controlled clinical study

Lyritis, George P.; Tsakalakos, N.; Magiasis, B.; Karachalios, Th.; Yiatzides, A.; Tsekoura, M.

doi:10.1007/bf02555844

Cited by 162 publications

(73 citation statements)

References 7 publications

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“…Calcitonin, given for 1-3 months following acute vertebral crush fracture, has been shown in several RCTs to decrease morbidity, improve remobilisation and prevent immobilisation bone loss. [125][126][127] The mechanism for the decrease in bone pain induced by calcitonin is not known for certain but may involve the release of endogenous endorphins. The use of calcitonin in this manner is beyond the scope of this review, which focuses upon its long-term use, but a small effect on bone pain is included in the quality-adjusted life-year (QALY) estimate (see chapter 3).…”

Section: Calcitoninmentioning

confidence: 99%

Treatment of established osteoporosis: a systematic review and cost-utility analysis

Kanis

Brazier

Stevenson

et al. 2002

Health Technol Assess

207

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Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. Contact Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to Direct Mail Works Ltd and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email.Paying by official purchase order You can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK.We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.hta.ac.uk/htacd.htm). Or contact Direct Mail Works (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA Programme and lists the membership of the various committees. HTA NHS R&D HTA ProgrammeT he NHS R&D Health Technology Assessment (HTA) Programme was set up in 1993 to ensure that high-quality research information on the costs, effectiveness and broader impact of health technologies is produced in the most efficient way for those who use, manage and provide care in the NHS.Initially, six HTA panels (pharmaceuticals, acute sector, primary and community care, diagnostics and imaging, population screening, methodology) helped to set the research priorities for the HTA Programme. However, during the past few years there have been a number of changes in and around NHS R&D, such as the establishment of the National Institute for Clinical Excellence (NICE) and the creation of three new research programmes: Service Delivery and Organisation (SDO); New and Emerging Applications of Technology (NEAT); and the Methodology Programme.This has meant that the HTA panels can now focus more explicitly on health technologies ('health technologies' are broadly defined to include all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care) rather than settings of care. Therefore the panel structure has been redefined and replaced by three new panels: Pharmaceuticals; Therapeutic Procedures (including devices and operations); and Diagnostic Technologies and Screening.The HTA Programme continues to commission both primary and secondary research. The HTA Commissioning Board, supported by the National Coordinating Centre for Health Technology Assessment (NCCHTA), will consider...

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Section: Calcitoninmentioning

confidence: 99%

Treatment of established osteoporosis: a systematic review and cost-utility analysis

Kanis

Brazier

Stevenson

et al. 2002

Health Technol Assess

207

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“…This is an approach used in early pharmacoeconomic evaluations. 88,99 Although the relationship between BMD and fracture risk is well established in untreated cohorts, the relationship between a change in BMD and change in fracture risk is less secure. 97,100,101 Indeed, recent RCT data indicate that treatment-induced changes in BMD may underestimate anti-fracture efficacy, i.e.…”

mentioning

confidence: 99%

Glucocorticoid-induced osteoporosis: a systematic review and cost-utility analysis

Kanis¹,

Stevenson²,

McCloskey³

et al. 2007

Health Technol Assess

134

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Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. NHS libraries can subscribe free of charge. Public libraries can subscribe at a very reduced cost of £100 for each volume (normally comprising 30-40 titles). The commercial subscription rate is £300 per volume. Please see our website for details. Subscriptions can only be purchased for the current or forthcoming volume. Contact details are as follows: Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to Direct Mail Works Ltd and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email. Paying by official purchase orderYou can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK. We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.hta.ac.uk/htacd.htm). Or contact Direct Mail Works (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA Programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment ProgrammeT he Health Technology Assessment (HTA) programme, now part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the costs, effectiveness and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined to include all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care, rather than settings of care. The research findings from the HTA Programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service'. The HTA Programme is needs-led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of projects. First is the commissioned route. Suggestions for research are actively sought from people working in the NHS, the public and consumer groups and professional bodies such as r...

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“…Um efeito interessante da calcitonina é sua ação analgésica, que a coloca como boa opção no tratamento do quadro doloroso agudo de fratura vertebral osteoporótica (9).…”

Section: Calcitoninaunclassified

Tratamento da osteoporose pós-menopausa

Leite

1999

Arq Bras Endocrinol Metab

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A osteoporose pós menopausa é a forma mais freqüente de osteoporose. Como a evolução da osteoporose é silenciosa, é importante a sua prevenção. A reposição hormonal é a indicação mais fisiológica para prevenção e tratamento. Comentamos as várias opções terapêu-ticas do tratamento da osteoporose pós menopausa em pacientes em que há contra-indicação ou recusa para TRH, não há resposta do metabolismo ósseo ao TRH ou quadro de osteoporose instalada. (Arq Bras Endocrinol Metab 1999; 43/6: 442-445) Unitermos: Osteoporose pós-menopausa; Alendronato; Caicitonina; Estrógeno ABSTRACT Postmenopausa osteoporosis is the most frequent type of osteoporosis. As its course is usually symptomless it is quite important the prevention of its complications. HRT is the most importante prevention measurement. In this paper other forms of therapeutics are discussed when HRT can not be utilized, or there is no adherence of the patient or lack of bone response to this treatment. No entanto, há situações clínicas em que necessitamos empregar outros recursos terapêuticos:1.quando há contra indicação de TRH ou a paciente se recusa a fazer TRH; 2.quando não há resposta do metabolismo ósseo ao TRH avaliada através de densitometria óssea e avaliação dos marcadores de remodelação óssea, após um ano do seu emprego; 3.quando o quadro clínico é de osteoporose estabelecida. Na situação 1, o emprego de outros recursos terapêuticos está indicado quando o exame densitométrico mostrar, a nível de coluna ou colo, valores DP inferiores a -2,5 D, quando houver fatores de risco ou quando a análise dos marcadores bioquímicos evidenciarem aumento de reabsorção que implicariam em perda óssea mais rápida.Nas situações 2 e 3, a terapêutica escolhida pode ser associada a TRH, visando os efeitos estrogênicos sobre outros parâmetros, como o cardiológico, psíquico, lipídico.Como a osteoporose pós-menopausa se caracteriza por alta remodelação, a terapêutica de escolha, nessas situações, seria o emprego de drogas que agem diminuindo a reabsorção óssea:

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Analgesic effect of Salmon calcitonin in osteoporotic vertebral fractures: A double-blind placebo-controlled clinical study

Cited by 162 publications

References 7 publications

Treatment of established osteoporosis: a systematic review and cost-utility analysis

Treatment of established osteoporosis: a systematic review and cost-utility analysis

Glucocorticoid-induced osteoporosis: a systematic review and cost-utility analysis

Tratamento da osteoporose pós-menopausa

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