Analgesic Effect of Bupivacaine Eluting Porcine Small Intestinal Submucosa (SIS) in Ferrets Undergoing Acute Abdominal Hernia Defect Surgery

Efficacy of oral transmucosal and intravenous administration of buprenorphine before surgery for postoperative analgesia in dogs undergoing ovariohysterectomy

“…In addition to palpation of the abdomen in phase 3 of the DIVAS, a palpometer g was used to provide data on pain in the abdomen after ovariohysterectomy. The palpometer has been successfully used in cats 22 for assessing pain after onychectomy and in ferrets 23 for assessing pain after abdominal hernia repair. The palpometer is a medical device that controls the pressure of manual palpation by measuring the pressure of the evaluator' s finger.…”

Bupivacaine-enhanced small intestinal submucosa biomaterial as a hernia repair device

“…Incorporation of bupivacaine into SIS provided pain relief following acute abdominal hernia defect repair in a ferret model. 20 The study described here was undertaken to evaluate the effect of bupivacaine incorporation on the tissue repair ability of SIS for ventral hernia repair. Bupivacaine was readily incorporated into SIS as demonstrated by elution studies.…”

Analgesic effect of intra-articularly administered morphine, dexmedetomidine, or a morphine-dexmedetomidine combination immediately following stifle joint surgery in dogs

“…16 Signs of pain were assessed in the following sequence: dogs were observed undisturbed, and signs of pain were assessed from outside of the cage or run; dogs were approached and spoken to, and behavior suggestive of pain was assessed; heart rate, respiratory rate, and blood pressure (measured with a Doppler ultrasound monitor) were assessed; and finally the stifle joint that had undergone surgery was palpated with a palpometer. [22][23][24] The general impression of pain consisted of a mean behavioral pain score (undisturbed behaviors and interactive behaviors, including the palpometer use) and a mean objective pain score (increase in heart rate, respiratory rate and systolic arterial blood pressure; Appendix 1). All dogs were continuously monitored visually for the first 4 hours following extubation.…”

“…This device has been used at the Purdue Veterinary Teaching Hospital as part of a pain assessment tool in dogs 22 and ferrets 24 and found to be effective in assessing signs of muscle and skin pain. This device has been used at the Purdue Veterinary Teaching Hospital as part of a pain assessment tool in dogs 22 and ferrets 24 and found to be effective in assessing signs of muscle and skin pain.…”