Analgesic Effect of a Herbal Medicine for Treatment of Primary Dysmenorrhea - A Double-blind Study

Kotani, Naoki; Oyama, Tsutomu; Sakai, Ichiro; Hashimoto, Hiroshi; Muraoka, Masahiro; Ogawa, Yasuhiro; Matsuki, Akitomo

doi:10.1142/s0192415x9700024x

Cited by 79 publications

(67 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Danggui-Shaoyao-San (DSS), also called Toki-shakuyaku-san or TJ-23, is a traditional Chinese medicinal prescription, used widely in oriental countries, such as China, Japan, and Korea (Fujii, 2002;Hagino, 1994;Higaki et al, 2002;Inanaga, 2007;Kotani et al, 1997). DSS was initially recorded in 'Synopsis of Prescriptions of the Golden Chamber', which was compiled by Zhong-Jing Zhang during the Han dynasty.…”

Section: Introductionmentioning

confidence: 99%

Danggui-Shaoyao-San and its active fraction JD-30 improve Aβ-induced spatial recognition deficits in mice

Hu¹,

Liu²,

Yuan³

et al. 2010

Journal of Ethnopharmacology

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Danggui-Shaoyao-San and its active fraction JD-30 improve Aβ-induced spatial recognition deficits in mice

Hu¹,

Liu²,

Yuan³

et al. 2010

Journal of Ethnopharmacology

View full text Add to dashboard Cite

“…The administration and safety of TS have been clinically established. It is often used for gynecological diseases [19,20]. There are some reports on climacteric symptoms [21] and improvement of luteal insufficiency [22].…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Hemiparesis in a Patient with an Intracerebral Hemorrhage at the Basal Ganglia, Thalamus, and Internal Capsule Treated with a Combination of Traditional Korean Medicine and Western Medicine

Ah-hyun¹,

최현민²,

Jiyoon³

et al. 2017

J Int Korean Med

View full text Add to dashboard Cite

In post-stroke patients, the recurrence of stroke and progression of impairments lead to a bedridden state and dementia. As for their treatments, only anti-hypertension and anti-coagulation therapies to prevent the recurrence of stroke are available. In Asia, post-stroke patients with impairments are often treated with herbal medicine. The present study evaluated the effectiveness of tokishakuyakusan (TS) in improving the impairment and independence in post-stroke patients. Thirty-one post-stroke patients (mean age = 81.4 years) were recruited and enrolled. Participants were randomly assigned to the TS group (n = 16) or nontreatment (control) group (n = 15) and treated for 12 months. Impairments were assessed using the Stroke Impairment Assessment Set (SIAS). Independence was evaluated using the functional independence measure (FIM). For each outcome measure, mean change was calculated every 3 months. The results were that impairments according to SIAS did not significantly change in the TS group. In contrast, SIAS significantly worsened in the control group. There was a significant difference between the two groups. In each term of SIAS, affected lower extremity scores, abdominal muscle strength, function of visuospatial perception, and so forth. in the TS group were better than those in the control group. Independence according to FIM did not change significantly in the TS group. In contrast, FIM significantly worsened in the control group. There was also a significant difference between the two groups. In conclusion, TS was considered to suppress the impairments of lower limbs and to exert a favorable effect on cerebral function for post-stroke patients.

show abstract

“…KSS has been known to possess anxiolytic effects in rats, an effect said to be mediated by the stimulation of the brain Á-aminobutyric acid A /benzodiazepine receptor [13]. Besides, TSS had an analgesic effect in women with dysmenorrhea [14] and antioxidant actions in the central nervous system [15], although to what extent these findings are related to climacteric symptoms is not known. In the light of the phytoestrogen contents in KSS and of the uncertainties surrounding the mechanisms of action of KSS/TSS, caution should be exerted when these two drugs are prescribed.…”

Section: Discussionmentioning

confidence: 99%

Treatment of Climacteric Symptoms with Herbal Formulas of Traditional Chinese Medicine

Pan

Kato²,

Sengoku³

et al. 2004

Gynecol Obstet Invest

View full text Add to dashboard Cite

Hormone replacement therapy (HRT) is not successful or is contraindicated for the treatment of climacteric symptoms in some patients. To investigate whether certain herbal formulas of traditional Chinese medicine (Kampo in Japanese) could be used as an alternative treatment, a longitudinal ‘before and after’ comparative study was carried out in 18 Japanese women, and the results were compared with those of 16 women who underwent HRT. Kampo improved all the climacteric symptoms. In contrast, improvement of cold limbs, sleeping disorders, shoulder stiffness/lumbago, and fatigue in the HRT group was either not significant or of limited extent. In addition, the serum level of estradiol in postmenopausal women was raised by the combined use of two Kampo formulas. These results suggest that Kampo may be considered an alternative to HRT for the treatment of climacteric symptoms, but vigorous monitoring for potential side effects of increased estrogen levels in some postmenopausal patients is needed.

show abstract

Analgesic Effect of a Herbal Medicine for Treatment of Primary Dysmenorrhea - A Double-blind Study

Cited by 79 publications

References 0 publications

Danggui-Shaoyao-San and its active fraction JD-30 improve Aβ-induced spatial recognition deficits in mice

Danggui-Shaoyao-San and its active fraction JD-30 improve Aβ-induced spatial recognition deficits in mice

A Case Report of Hemiparesis in a Patient with an Intracerebral Hemorrhage at the Basal Ganglia, Thalamus, and Internal Capsule Treated with a Combination of Traditional Korean Medicine and Western Medicine

Treatment of Climacteric Symptoms with Herbal Formulas of Traditional Chinese Medicine

Contact Info

Product

Resources

About