Analgesic, Antipyretic and Ulcerogenic Effects of Indian Ayurvedic Herbal Formulation Triphala

Sabina, Evan Prince; Rasool, Mahaboob Khan

doi:10.3923/rjmp.2007.54.59

Cited by 7 publications

(1 citation statement)

References 8 publications

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“…When these activities of Triphala (500/1000 mg/kg body wt) were compared with then non-steroidal antiinflammatory drug Indomethacin (10 mg/kg body wt) on the experimental models in mice, it was seen that Triphala produced excellent analgesic and antipyretic effect at both the dose levels, without any gastric injury. 37 The analgesic action of the Triphala is attributed to the blockade of the effect or release of the endogenous substances that stimulate pain nerve endings as seen in non-steroidal anti-inflammatory drugs. 38 Triphala extract ointment (10%w/w) also shows strong antibacterial, wound healing, and antioxidant activities during the management of infected wounds in rat model.…”

Section: Analgesic Antipyretic and Ulcerogenic Activitiesmentioning

confidence: 99%

Triphala: Envisioning Its Role in Dentistry

Bhavikatti¹,

Dhamija²,

Mlv³

2015

Int. Res. J. Pharm.

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Triphala is an important rasayana drug, used since time immemorial and described in the Ayurveda as a "tridoshic rasayana" (Charka 1500 BC), having balancing and rejuvenating effects on the three constitutional elements that govern human life (vata, pitta, and kapha). The synergy of the three "fruits" (Amalaki-Phyllanthus emblica, Bibhitaki-Terminalia belerica, and Haritaki-Terminalia chebula) produces the tonifying, detoxifying, mildly antiseptic, rejuvenative and laxative effects of this classic formulation. Such a wide array of actions of triphala is supposed to be because of the 47 tannins and 35 phytochemicals which have been so far isolated from it. In Ayurveda, Triphala holds a paramount position as, naturally; many illnesses require first to be treated with purificatory therapy. In recent times, Triphala is being widely studied and researched in the dental arena for its anti-caries, antioxidant, anti-collagenase, and anti-microbial activities. This review on Triphala throws an inclusive limelight on the properties of Triphala and its numerous applications in dentistry.

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Section: Analgesic Antipyretic and Ulcerogenic Activitiesmentioning

confidence: 99%

Triphala: Envisioning Its Role in Dentistry

Bhavikatti¹,

Dhamija²,

Mlv³

2015

Int. Res. J. Pharm.

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Studies on Prokinetic, Laxative and Spasmodic Activities ofPhyllanthus emblicain Experimental Animals

Mehmood

Rehman

et al. 2012

Phytotherapy Research

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This study was aimed to provide pharmacological basis for the medicinal use of Phyllanthus emblica fruit in indigestion and constipation using the in-vivo and in-vitro assays. The crude extract of the dried fruits of Phyllanthus emblica (Pe.Cr) and its fractions were tested positive for alkaloids, saponins, tannins, terpenes, flavonoids, sterols and coumarins. Pe.Cr at the doses of 100 and 300 mg/kg exhibited the prokinetic and laxative activities in mice, which were found partially sensitive to atropine. In isolated guinea-pig ileum and rabbit jejunum, the crude extract and its aqueous fraction (Pe.Aq) caused concentration-dependent and partially atropine-sensitive stimulatory effects followed by relaxation at higher tested concentrations, being more efficacious in guinea pig, while more potent in rabbit tissues. The petroleum fraction (0.003-0.1 mg/mL) exhibited fully atropine-sensitive contractions in both guinea-pig and rabbit tissues. However, the ethyl acetate and chloroform fractions (0.003-1.0 mg/mL) showed only spasmolytic activity when studied in spontaneously contracting rabbit jejunum. This study showed that the Phyllanthus emblica possesses prokinetic and laxative activities in mice along with spasmodic effect in the isolated tissues of guinea pig and rabbit, mediated partially through activation of muscarinic receptors; thus, this study provides a rationale for the medicinal use of Phyllanthus emblica fruits in indigestion and constipation.

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A validated quantification of gallic acid and ellagic acid in Triphala using a high-performance thin-layer chromatography method

Pallavi

Jha

2021

JPC-J Planar Chromat

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Analgesic, Antipyretic and Ulcerogenic Effects of Indian Ayurvedic Herbal Formulation Triphala

Cited by 7 publications

References 8 publications

Triphala: Envisioning Its Role in Dentistry

Triphala: Envisioning Its Role in Dentistry

Studies on Prokinetic, Laxative and Spasmodic Activities ofPhyllanthus emblicain Experimental Animals

A validated quantification of gallic acid and ellagic acid in Triphala using a high-performance thin-layer chromatography method

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