Analgesic, anti-inflammatory, anticonvulsant and CNS effect of the ethanolic extract of Butea monosperma roots

Arefin, Shah Md Anisul; Islam, A. K. M. R.; Rashid, Syeda Tahmina Binte; Rayhan, Abu; Hossen, Monir; Alam, Jahir; Shahriar, Mohammad

doi:10.3329/jujbs.v4i1.27781

Cited by 4 publications

(1 citation statement)

References 24 publications

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“…This plant exhibited notable anti- inflammatory activities in several in vitro and in vivo studies. For instance, fixed oil from B. monosperma seed attenuated carrageenan induced paw edema in rats [72], flower extracts inhibited inflammatory mediators like IL-1β, IL-6 and IL-8, prostaglandin E2 production and MMP-1, -2, -9 and -10 secretion as well as carrageenan induced paw edema and cotton pellet implanted granuloma in rats [73][74][75]. Extracts from this plant have also been found to protect RBC membrane from lysis [76,77].…”

Section: Asparagus Racemosus Willdmentioning

confidence: 99%

Management of inflammatory disorders: A brief review of selected ethnomedicinal plants

Akhtar,

Khan,

Zahan

2023

JPP

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Medicinal plants have immense significance to treat various diseases and have great potential to discover and develop new therapies. This paper aims to summarize the in vitro and in vivo investigations conducted to evaluate the anti-inflammatory activities of selected medicinal plants of Bangladesh. The anti-inflammatory active molecules reported from those selected plants have also been highlighted. The species included in this review are Abelmoschus esculentus (L.) Moench, Asparagus racemosus Willd., Blumea lacera (Burm.f.) DC., Butea monosperma (Lam.) Taub., Cheilocostus speciosus (J.Koenig) C.D.Specht., Mussaenda roxburghii Hook. f., Anthocephalus cadamba (Roxb.) Miq., Phyllanthus reticulatus Poir., Sesbania grandiflora (L.) Pers. and Spondias pinnata (L. f.) Kurz. The toxic effect of these plants has also been included briefly. We hope that this overview will shed some light on the function of these plants and their molecules in the treatment of various inflammatory diseases and will attract the attention of investigators interested in designing novel therapeutic approaches.

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Section: Asparagus Racemosus Willdmentioning

confidence: 99%

Management of inflammatory disorders: A brief review of selected ethnomedicinal plants

Akhtar,

Khan,

Zahan

2023

JPP

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Ethnobotany, Phytochemistry and Pharmacology of Palash (Butea monosperma (Lam.) Taub.): a Systematic Review

et al. 2022

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Anti-Inflammatory Medicinal Plants of Bangladesh—A Pharmacological Evaluation

Akhtar

2022

Front. Pharmacol.

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Inflammatory diseases are considered major threats to human health worldwide. In Bangladesh, a number of medicinal plants have been used in traditional medicine from time immemorial in the treatment of diverse diseases, including inflammatory disorders. This assignment aims at providing the status of the medicinal plants of Bangladesh which are traditionally used in the management of inflammatory disorders and are investigated for their anti-inflammatory prospects using different preclinical studies and future research directions. The information of medicinal plants assembled in this review was obtained from a literature search of electronic databases such as Google Scholar, PubMed, Scopus, Web of Science and ScienceDirect up to December, 2020 from publications on plants investigated for their anti-inflammatory activities, in which the place of plant sample collection was identified as Bangladesh. Keywords for primary searches were “anti-inflammatory,” “Bangladeshi,” and “medicinal plants.” Criteria followed to include plant species were plants that showed significant anti-inflammatory activities in 1) two or more sets of experiments in a single report, 2) same or different sets of experiments in two or more reports, and, 3) plants which are traditionally used in the treatment of inflammation and inflammatory disorders. In this study, 48 species of medicinal plants have been reviewed which have been used in traditional healing practices to manage inflammatory disorders in Bangladesh. The mechanistic pathways of the in vivo and in vitro study models used for the evaluation of anti-inflammatory properties of plant samples have been discussed. Selected plants were described in further detail for their habitat, anti-inflammatory studies conducted in countries other than Bangladesh, and anti-inflammatory active constituents isolated from these plants if any. Medicinal plants of Bangladesh have immense significance for anti-inflammatory activity and have potential to contribute toward the discovery and development of novel therapeutic approaches to combat diseases associated with inflammation. However, the plants reviewed in this article had chiefly undergone preliminary screening and require substantial investigations including identification of active molecules, understanding the mechanism of action, and evaluation for safety and efficacy to be followed by the formulation of safe and effective drug products.

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Analgesic, anti-inflammatory, anticonvulsant and CNS effect of the ethanolic extract of Butea monosperma roots

Cited by 4 publications

References 24 publications

Management of inflammatory disorders: A brief review of selected ethnomedicinal plants

Management of inflammatory disorders: A brief review of selected ethnomedicinal plants

Ethnobotany, Phytochemistry and Pharmacology of Palash (Butea monosperma (Lam.) Taub.): a Systematic Review

Anti-Inflammatory Medicinal Plants of Bangladesh—A Pharmacological Evaluation

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