Analgesic, anti-inflammatory and antipyretic activities of the petroleum ether fraction from the ethanol extract of Desmodium podocarpum

Beneficial effects of methanolic extract of Indigofera linnaei Ali. on the inflammatory and nociceptive responses in rodent models

“…Some analgesic drugs such as aspirin usually have few effects in the hot plate test indicating their peripheral analgesic activities. But some other analgesic drugs such as ibuprofen and morphine can decrease prostaglandin synthesis via central inhibition of cyclooxygenase (Zhu et al, 2011) or bind to specific opioid receptors in the central nervous system, exhibiting both their peripheral and central analgesic activities. However, the hot plate test was undertaken to verify if MEIL would have any central analgesic effect and the results are presented in Table VI.…”

Antipyretic Properties of Methanol Stem Bark Extracts of Acacia hockii De Wild and Kigelia africana (Lam) Benth in Wistar Rats

“…Subcutaneous injection of steam distilled turpentine causes pyrexia by enhancing the production of PGE 2 which ultimately increase the body temperature [24]. The turpentine-induced pyrexia has been established to be fast, has persistent fever pattern and experimental animals have a high tolerance to turpentine compared to other exogenous pyrogens [21,25].…”

Antipyretic and anticonvulsant activity of n-hexane fraction of Viola betonicifolia

“…The inhibition of prostaglandin synthesis could be the possible mechanism of antipyretic action as that of paracetamol and the inhibition of prostaglandin can be achieved by blocking the cyclooxygenase enzyme activity. There are several mediators for pyrexia that regulates the body temperature by interacting with the thermo-regulatory system in the CNS and the inhibition of these mediators is responsible for the antipyretic effect [13] .…”