Analgesic and anti‐inﬂammatory activity of the leaf essential oil of Laurus nobilis Linn.

Sayyah, Mohammad; Saroukhani, G.; Peirovi, A.; Kamalinejad, Mohammad

doi:10.1002/ptr.1197

Cited by 94 publications

(68 citation statements)

References 7 publications

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“…For example eugenol the major essential oil of Gundelia tournefortii (9.5 %) has been shown to possess anti-inflammatory, antioxidant, anaesthetic and muscle relaxant properties [25]. Previous study showed that eugenol exhibits antinociceptive effects through different mechanisms that may involve both central and peripheral pathway, One of these mechanisms, is via blockade of calcium channels and vanilloid receptor modulation [26].…”

Section: Discussionmentioning

confidence: 99%

Chemical composition and antinociceptive effects of essential oil from aerial parts of Gundelia tournefortii L Asteraceae (Compositae) in rats

Qnais¹,

Bseiso²,

Wedyan³

et al. 2016

Trop. J. Pharm Res

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Section: Discussionmentioning

confidence: 99%

Chemical composition and antinociceptive effects of essential oil from aerial parts of Gundelia tournefortii L Asteraceae (Compositae) in rats

Qnais¹,

Bseiso²,

Wedyan³

et al. 2016

Trop. J. Pharm Res

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“…The essential oil of the leaves of L. noblis has been known to contain 1,8-cineole, linalool, α-terpinyl acetate and several terpenes (5,24). The leaves of L. noblis were stored at 4°C before performing experiments.…”

Section: Methodsmentioning

confidence: 99%

“…The dried leaves of L. noblis are used as a spice or flavoring agent in the culinary and food industries. The essential oil prepared from the leaves has been reported to have antibacterial, antioxidant and antiinflammatory activities (5,24). The leaves of L. noblis have been also used to treat rheumatism, neuralgia and scabies in Japanese folk medicine (14,21).…”

mentioning

confidence: 99%

Volatiles emitted from the leaves of Laurus nobilis L. improve vigilance performance in visual discrimination task

et al. 2011

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The leaves of Laurus noblis L. (laurel) are mainly used as a spice in cooking, and the essential oil obtained by steam distillation of the leaves is used as an additive in foods, drugs and cosmetics. We investigated the effect of the volatiles emitted from the leaves of L. noblis at different doses (low-dose and high-dose groups) on vigilance performance in a visual discrimination task. By inhaling volatiles of the leaves of L. noblis, the decrease of the rate of true hits found in the control group was prevented in the low-dose group. The high-dose group showed higher scores than the low-dose group for subjective effects related to negative emotion. Meanwhile, both groups showed physiological effects suggesting stimulation of circulation. These findings suggest that the volatiles emitted from the leaves of L. noblis at low concentration could be utilized to maintain a high level of vigilance performance, such as the rate of true hits by improving physiological arousal without incurring the detrimental performance effects of negative emotion.

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“…14,15 The antimicrobial, analgesic, anti-inflammatory, acetylcholine esterase inhibiting properties of the essential oil of Laurus nobilis L. have been reported. 15,16 There are four reports on the essential oil content and composition of Origanum vulgare L, spp. hirtum of Turkish origin.…”

Section: Introductionmentioning

confidence: 99%

Investigation of antimicrobial activities of some herbs containing essential oils and their mouthwash formulations

Kulaksiz

Okur

et al. 2018

tjps

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Amaç: Türkiye'de halk arasında yaygın olarak kullanılan bitkilerden elde edilen uçucu yağların antimikrobiyal etkilerini araştırmak ve bu etkilerden yola çıkarak ağız enfeksiyonlarında kullanılmak üzere gargara formülasyonu hazırlamaktır. Gereç ve Yöntemler: Uçucu yağlar, bitkilerden (Origanum vulgare L. spp. hirtum, Rosmarinus officinalis L., Laurus nobilis L., Salvia fruticosa Mill.) su distilasyonu metodu ile Clevenger apareyi kullanılarak elde edilmiştir. Elde edilen uçucu yağlar ve %4,5 ve %9,0 oranlarında uçucu yağların karışımını içeren gargara formülasyonlarının antimikrobiyal aktiviteleri disk difüzyon metodu ve mikrobroth dilüsyon metodu ile araştırılmıştır. Bulgular: Bu çalışmada antimikrobiyal aktivite disk difüzyon metodu ve mikrobroth dilüsyon metoduyla değerlendirilmiştir. İnhibisyon zon çaplarının 7-59 mm arasında değişkenlik gösterdiği belirlenmiştir. Uçucu yağlar, mikroorganizmalar üzerine saf olarak uygulandığında statik ve sidal etkinliğin genellikle %50 ve %50'nin üzerinde olduğu gözlenmiştir. %4,5 oranında uçucu yağ karışımı içeren F2 formülasyonunun Staphylococcus aureus ATCC 25923 üzerindeki minimum bakterisidal etkisinin %6,25 olduğu ve diğer tüm mikroorganizmalar üzerinde minimum inhibitör konsantrasyon ve minimum bakterisidal konsantrasyonunun %3,125 olduğu bulunmuştur. Uçucu yağ örneklerinin mikroorganizmalar üzerine saf olarak Objectives: The aim of this study was to prepare pharmaceutical formulations of mouthwashes and examine the antimicrobial activities of essential oils obtained from plants used traditionally in Turkey for oral infections. Materials and Methods: Essential oils were obtained from herbal drugs with water distillation method using of Clevenger apparatus. Antimicrobial capacities of mouthwash formulations containing mixture of essential oils with proportions of 4.5% and 9.0% were examined by disc diffusion method and microbroth dilution method. Results: In study, antimicrobial activity was evaluated by disc diffusion method and microbroth dilution method. The inhibition zone diameters were determined to vary between 7-59 mm. It has been observed that the static and cidal activity was generally 50% and greater than 50%, when pure essential oil samples were applied on microorganism specimens. Formulation F2 containing mixture of essential oils with proportions of 4.5%, showed 6.25% minimum bactericidal effect on Staphylococcus aureus ATCC 25923 and 3.125% the minimum inhibitor concentration and minimum bactericidal concentration on all other microorganisms. It is found that the antimicrobial effect of pure essential oil samples applied on microorganisms, was lower than mouthwashes formulations; the antimicrobial effect of F2 formulation containing mixture of essential oils with proportions of 4.5% was higher than formulation F1 containing mixture of essential oils with proportions of 9%. Conclusion:The results obtained by these methods allow us to conclude that the essential oils and prepared F1 and F2 mouthwash formulations exert activity against microorganis...

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Analgesic and anti‐inﬂammatory activity of the leaf essential oil of Laurus nobilis Linn.

Cited by 94 publications

References 7 publications

Chemical composition and antinociceptive effects of essential oil from aerial parts of <i>Gundelia tournefortii</i> L Asteraceae (Compositae) in rats

Chemical composition and antinociceptive effects of essential oil from aerial parts of <i>Gundelia tournefortii</i> L Asteraceae (Compositae) in rats

Volatiles emitted from the leaves of Laurus nobilis L. improve vigilance performance in visual discrimination task

Investigation of antimicrobial activities of some herbs containing essential oils and their mouthwash formulations

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