2018
DOI: 10.3329/dujps.v17i1.37116
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Analgesic Activity of Methanolic Extract of Tubers of Arisaema tortuosum (Wall.) Schott. in Swiss Albino Mice

Abstract: ABSTRACT:The aim of the the present study was to investigate the analgesic activity of methanolic extract of Arisaema tortuosum (MEAT) using acetic acid-induced writhing and hot plate methods. The hot plate method is useful in elucidating centrally mediated antinociceptive responses, while acetic acid-induced writhing is the chemically induced pain of peripheral origin. The MEAT was used at doses of 50, 100, 200 and 400 mg/kg body weight on swiss albino mice. The percentage inhibition of the abdominal constric… Show more

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Cited by 6 publications
(4 citation statements)
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“…Zhao and collab., found a new piperidine alkaloid in rhizome of Arisaema decipiens [ZHAO et al, 2010] . Recently, Chakraborty and collab., have proved analgesic activity of methanolic extract of tubers of Arisaema tortuosum [CHAKRABORTY et al, 2018] . From the above research status, we do hope that this study will be a platform for further studies on the phytochemical composition in ethanolic extract from rhizome of A. langbiangense, a rare and endemic species of Vietnam with the aim to apply this species into practice in the future.…”
Section: Figure 2 Chromatogram (Lc-ms) Of the Ethanol Extract Of A Langbiangense Rhizomes Obtained By Macerationmentioning
confidence: 96%
“…Zhao and collab., found a new piperidine alkaloid in rhizome of Arisaema decipiens [ZHAO et al, 2010] . Recently, Chakraborty and collab., have proved analgesic activity of methanolic extract of tubers of Arisaema tortuosum [CHAKRABORTY et al, 2018] . From the above research status, we do hope that this study will be a platform for further studies on the phytochemical composition in ethanolic extract from rhizome of A. langbiangense, a rare and endemic species of Vietnam with the aim to apply this species into practice in the future.…”
Section: Figure 2 Chromatogram (Lc-ms) Of the Ethanol Extract Of A Langbiangense Rhizomes Obtained By Macerationmentioning
confidence: 96%
“…Ethanolic extracts (100,300, and 500 mg/kg, IP) of Pueraria tuberosa were employed as a positive control (paracetamol, 10 mg/kg). The latency was measured before and after intraperitoneal injection of 100, 300 and 500 mg/kg of each extract to different groups of six mice for 15, 30, 60, and 120 minutes [11][12] . The percentage variance was computed by multiplying the average reaction times by the following ratio: 115…”
Section: Pharmacological Evaluationmentioning
confidence: 99%
“…The central analgesic activity was determined by tail immersion method following the method described by Chakraborty et al (2018) using diclofenac sodium as a positive control.…”
Section: Central Analgesic Activitymentioning
confidence: 99%